Message d'erreur

  • Notice: Undefined index: date in biocodex_preprocess_taxonomy_term() (line 1205 of themes/biocodex/biocodex.theme).
    biocodex_preprocess_taxonomy_term(Array, 'taxonomy_term', Array) (Line: 287)
    Drupal\Core\Theme\ThemeManager->render('taxonomy_term', Array) (Line: 435)
    Drupal\Core\Render\Renderer->doRender(Array) (Line: 448)
    Drupal\Core\Render\Renderer->doRender(Array, ) (Line: 195)
    Drupal\Core\Render\Renderer->render(Array) (Line: 490)
    Drupal\Core\Template\TwigExtension->escapeFilter(Object, Array, 'html', NULL, 1) (Line: 48)
    __TwigTemplate_ebe7487260f51065d753fb1b4e68981ba492d81515793ddfbe52ade06d7f8f01->doDisplay(Array, Array) (Line: 379)
    Twig_Template->displayWithErrorHandling(Array, Array) (Line: 347)
    Twig_Template->display(Array) (Line: 358)
    Twig_Template->render(Array) (Line: 64)
    twig_render_template('themes/biocodex/templates/views/views-view.html.twig', Array) (Line: 384)
    Drupal\Core\Theme\ThemeManager->render(Array, Array) (Line: 435)
    Drupal\Core\Render\Renderer->doRender(Array) (Line: 448)
    Drupal\Core\Render\Renderer->doRender(Array, ) (Line: 195)
    Drupal\Core\Render\Renderer->render(Array, ) (Line: 226)
    Drupal\Core\Render\MainContent\HtmlRenderer->Drupal\Core\Render\MainContent\{closure}() (Line: 574)
    Drupal\Core\Render\Renderer->executeInRenderContext(Object, Object) (Line: 227)
    Drupal\Core\Render\MainContent\HtmlRenderer->prepare(Array, Object, Object) (Line: 117)
    Drupal\Core\Render\MainContent\HtmlRenderer->renderResponse(Array, Object, Object) (Line: 90)
    Drupal\Core\EventSubscriber\MainContentViewSubscriber->onViewRenderArray(Object, 'kernel.view', Object) (Line: 111)
    Drupal\Component\EventDispatcher\ContainerAwareEventDispatcher->dispatch('kernel.view', Object) (Line: 149)
    Symfony\Component\HttpKernel\HttpKernel->handleRaw(Object, 1) (Line: 64)
    Symfony\Component\HttpKernel\HttpKernel->handle(Object, 1, 1) (Line: 57)
    Drupal\Core\StackMiddleware\Session->handle(Object, 1, 1) (Line: 47)
    Drupal\Core\StackMiddleware\KernelPreHandle->handle(Object, 1, 1) (Line: 207)
    Drupal\page_cache\StackMiddleware\PageCache->fetch(Object, 1, 1) (Line: 121)
    Drupal\page_cache\StackMiddleware\PageCache->lookup(Object, 1, 1) (Line: 75)
    Drupal\page_cache\StackMiddleware\PageCache->handle(Object, 1, 1) (Line: 47)
    Drupal\Core\StackMiddleware\ReverseProxyMiddleware->handle(Object, 1, 1) (Line: 50)
    Drupal\Core\StackMiddleware\NegotiationMiddleware->handle(Object, 1, 1) (Line: 23)
    Stack\StackedHttpKernel->handle(Object, 1, 1) (Line: 656)
    Drupal\Core\DrupalKernel->handle(Object) (Line: 19)
    
  • Notice: Undefined index: date in biocodex_preprocess_taxonomy_term() (line 1206 of themes/biocodex/biocodex.theme).
    biocodex_preprocess_taxonomy_term(Array, 'taxonomy_term', Array) (Line: 287)
    Drupal\Core\Theme\ThemeManager->render('taxonomy_term', Array) (Line: 435)
    Drupal\Core\Render\Renderer->doRender(Array) (Line: 448)
    Drupal\Core\Render\Renderer->doRender(Array, ) (Line: 195)
    Drupal\Core\Render\Renderer->render(Array) (Line: 490)
    Drupal\Core\Template\TwigExtension->escapeFilter(Object, Array, 'html', NULL, 1) (Line: 48)
    __TwigTemplate_ebe7487260f51065d753fb1b4e68981ba492d81515793ddfbe52ade06d7f8f01->doDisplay(Array, Array) (Line: 379)
    Twig_Template->displayWithErrorHandling(Array, Array) (Line: 347)
    Twig_Template->display(Array) (Line: 358)
    Twig_Template->render(Array) (Line: 64)
    twig_render_template('themes/biocodex/templates/views/views-view.html.twig', Array) (Line: 384)
    Drupal\Core\Theme\ThemeManager->render(Array, Array) (Line: 435)
    Drupal\Core\Render\Renderer->doRender(Array) (Line: 448)
    Drupal\Core\Render\Renderer->doRender(Array, ) (Line: 195)
    Drupal\Core\Render\Renderer->render(Array, ) (Line: 226)
    Drupal\Core\Render\MainContent\HtmlRenderer->Drupal\Core\Render\MainContent\{closure}() (Line: 574)
    Drupal\Core\Render\Renderer->executeInRenderContext(Object, Object) (Line: 227)
    Drupal\Core\Render\MainContent\HtmlRenderer->prepare(Array, Object, Object) (Line: 117)
    Drupal\Core\Render\MainContent\HtmlRenderer->renderResponse(Array, Object, Object) (Line: 90)
    Drupal\Core\EventSubscriber\MainContentViewSubscriber->onViewRenderArray(Object, 'kernel.view', Object) (Line: 111)
    Drupal\Component\EventDispatcher\ContainerAwareEventDispatcher->dispatch('kernel.view', Object) (Line: 149)
    Symfony\Component\HttpKernel\HttpKernel->handleRaw(Object, 1) (Line: 64)
    Symfony\Component\HttpKernel\HttpKernel->handle(Object, 1, 1) (Line: 57)
    Drupal\Core\StackMiddleware\Session->handle(Object, 1, 1) (Line: 47)
    Drupal\Core\StackMiddleware\KernelPreHandle->handle(Object, 1, 1) (Line: 207)
    Drupal\page_cache\StackMiddleware\PageCache->fetch(Object, 1, 1) (Line: 121)
    Drupal\page_cache\StackMiddleware\PageCache->lookup(Object, 1, 1) (Line: 75)
    Drupal\page_cache\StackMiddleware\PageCache->handle(Object, 1, 1) (Line: 47)
    Drupal\Core\StackMiddleware\ReverseProxyMiddleware->handle(Object, 1, 1) (Line: 50)
    Drupal\Core\StackMiddleware\NegotiationMiddleware->handle(Object, 1, 1) (Line: 23)
    Stack\StackedHttpKernel->handle(Object, 1, 1) (Line: 656)
    Drupal\Core\DrupalKernel->handle(Object) (Line: 19)
    
  • Notice: Undefined index: keywords in biocodex_preprocess_taxonomy_term() (line 1207 of themes/biocodex/biocodex.theme).
    biocodex_preprocess_taxonomy_term(Array, 'taxonomy_term', Array) (Line: 287)
    Drupal\Core\Theme\ThemeManager->render('taxonomy_term', Array) (Line: 435)
    Drupal\Core\Render\Renderer->doRender(Array) (Line: 448)
    Drupal\Core\Render\Renderer->doRender(Array, ) (Line: 195)
    Drupal\Core\Render\Renderer->render(Array) (Line: 490)
    Drupal\Core\Template\TwigExtension->escapeFilter(Object, Array, 'html', NULL, 1) (Line: 48)
    __TwigTemplate_ebe7487260f51065d753fb1b4e68981ba492d81515793ddfbe52ade06d7f8f01->doDisplay(Array, Array) (Line: 379)
    Twig_Template->displayWithErrorHandling(Array, Array) (Line: 347)
    Twig_Template->display(Array) (Line: 358)
    Twig_Template->render(Array) (Line: 64)
    twig_render_template('themes/biocodex/templates/views/views-view.html.twig', Array) (Line: 384)
    Drupal\Core\Theme\ThemeManager->render(Array, Array) (Line: 435)
    Drupal\Core\Render\Renderer->doRender(Array) (Line: 448)
    Drupal\Core\Render\Renderer->doRender(Array, ) (Line: 195)
    Drupal\Core\Render\Renderer->render(Array, ) (Line: 226)
    Drupal\Core\Render\MainContent\HtmlRenderer->Drupal\Core\Render\MainContent\{closure}() (Line: 574)
    Drupal\Core\Render\Renderer->executeInRenderContext(Object, Object) (Line: 227)
    Drupal\Core\Render\MainContent\HtmlRenderer->prepare(Array, Object, Object) (Line: 117)
    Drupal\Core\Render\MainContent\HtmlRenderer->renderResponse(Array, Object, Object) (Line: 90)
    Drupal\Core\EventSubscriber\MainContentViewSubscriber->onViewRenderArray(Object, 'kernel.view', Object) (Line: 111)
    Drupal\Component\EventDispatcher\ContainerAwareEventDispatcher->dispatch('kernel.view', Object) (Line: 149)
    Symfony\Component\HttpKernel\HttpKernel->handleRaw(Object, 1) (Line: 64)
    Symfony\Component\HttpKernel\HttpKernel->handle(Object, 1, 1) (Line: 57)
    Drupal\Core\StackMiddleware\Session->handle(Object, 1, 1) (Line: 47)
    Drupal\Core\StackMiddleware\KernelPreHandle->handle(Object, 1, 1) (Line: 207)
    Drupal\page_cache\StackMiddleware\PageCache->fetch(Object, 1, 1) (Line: 121)
    Drupal\page_cache\StackMiddleware\PageCache->lookup(Object, 1, 1) (Line: 75)
    Drupal\page_cache\StackMiddleware\PageCache->handle(Object, 1, 1) (Line: 47)
    Drupal\Core\StackMiddleware\ReverseProxyMiddleware->handle(Object, 1, 1) (Line: 50)
    Drupal\Core\StackMiddleware\NegotiationMiddleware->handle(Object, 1, 1) (Line: 23)
    Stack\StackedHttpKernel->handle(Object, 1, 1) (Line: 656)
    Drupal\Core\DrupalKernel->handle(Object) (Line: 19)
    
  • Notice: Undefined index: from in biocodex_preprocess_page() (line 938 of themes/biocodex/biocodex.theme).
    biocodex_preprocess_page(Array, 'page', Array) (Line: 287)
    Drupal\Core\Theme\ThemeManager->render('page', Array) (Line: 435)
    Drupal\Core\Render\Renderer->doRender(Array, ) (Line: 195)
    Drupal\Core\Render\Renderer->render(Array) (Line: 490)
    Drupal\Core\Template\TwigExtension->escapeFilter(Object, Array, 'html', NULL, 1) (Line: 302)
    __TwigTemplate_ca4e890221b05d8eb544a486608af4724c44a8b112ef7a47902661d29a187ea6->doDisplay(Array, Array) (Line: 379)
    Twig_Template->displayWithErrorHandling(Array, Array) (Line: 347)
    Twig_Template->display(Array) (Line: 358)
    Twig_Template->render(Array) (Line: 64)
    twig_render_template('themes/biocodex/templates/html.html.twig', Array) (Line: 384)
    Drupal\Core\Theme\ThemeManager->render('html', Array) (Line: 435)
    Drupal\Core\Render\Renderer->doRender(Array, ) (Line: 195)
    Drupal\Core\Render\Renderer->render(Array) (Line: 147)
    Drupal\Core\Render\MainContent\HtmlRenderer->Drupal\Core\Render\MainContent\{closure}() (Line: 574)
    Drupal\Core\Render\Renderer->executeInRenderContext(Object, Object) (Line: 148)
    Drupal\Core\Render\MainContent\HtmlRenderer->renderResponse(Array, Object, Object) (Line: 90)
    Drupal\Core\EventSubscriber\MainContentViewSubscriber->onViewRenderArray(Object, 'kernel.view', Object) (Line: 111)
    Drupal\Component\EventDispatcher\ContainerAwareEventDispatcher->dispatch('kernel.view', Object) (Line: 149)
    Symfony\Component\HttpKernel\HttpKernel->handleRaw(Object, 1) (Line: 64)
    Symfony\Component\HttpKernel\HttpKernel->handle(Object, 1, 1) (Line: 57)
    Drupal\Core\StackMiddleware\Session->handle(Object, 1, 1) (Line: 47)
    Drupal\Core\StackMiddleware\KernelPreHandle->handle(Object, 1, 1) (Line: 207)
    Drupal\page_cache\StackMiddleware\PageCache->fetch(Object, 1, 1) (Line: 121)
    Drupal\page_cache\StackMiddleware\PageCache->lookup(Object, 1, 1) (Line: 75)
    Drupal\page_cache\StackMiddleware\PageCache->handle(Object, 1, 1) (Line: 47)
    Drupal\Core\StackMiddleware\ReverseProxyMiddleware->handle(Object, 1, 1) (Line: 50)
    Drupal\Core\StackMiddleware\NegotiationMiddleware->handle(Object, 1, 1) (Line: 23)
    Stack\StackedHttpKernel->handle(Object, 1, 1) (Line: 656)
    Drupal\Core\DrupalKernel->handle(Object) (Line: 19)
    
  • Notice: Undefined index: from in biocodex_preprocess_page() (line 938 of themes/biocodex/biocodex.theme).
    biocodex_preprocess_page(Array, 'page', Array) (Line: 287)
    Drupal\Core\Theme\ThemeManager->render('page', Array) (Line: 435)
    Drupal\Core\Render\Renderer->doRender(Array, ) (Line: 195)
    Drupal\Core\Render\Renderer->render(Array) (Line: 490)
    Drupal\Core\Template\TwigExtension->escapeFilter(Object, Array, 'html', NULL, 1) (Line: 302)
    __TwigTemplate_ca4e890221b05d8eb544a486608af4724c44a8b112ef7a47902661d29a187ea6->doDisplay(Array, Array) (Line: 379)
    Twig_Template->displayWithErrorHandling(Array, Array) (Line: 347)
    Twig_Template->display(Array) (Line: 358)
    Twig_Template->render(Array) (Line: 64)
    twig_render_template('themes/biocodex/templates/html.html.twig', Array) (Line: 384)
    Drupal\Core\Theme\ThemeManager->render('html', Array) (Line: 435)
    Drupal\Core\Render\Renderer->doRender(Array, ) (Line: 195)
    Drupal\Core\Render\Renderer->render(Array) (Line: 147)
    Drupal\Core\Render\MainContent\HtmlRenderer->Drupal\Core\Render\MainContent\{closure}() (Line: 574)
    Drupal\Core\Render\Renderer->executeInRenderContext(Object, Object) (Line: 148)
    Drupal\Core\Render\MainContent\HtmlRenderer->renderResponse(Array, Object, Object) (Line: 90)
    Drupal\Core\EventSubscriber\MainContentViewSubscriber->onViewRenderArray(Object, 'kernel.view', Object) (Line: 111)
    Drupal\Component\EventDispatcher\ContainerAwareEventDispatcher->dispatch('kernel.view', Object) (Line: 149)
    Symfony\Component\HttpKernel\HttpKernel->handleRaw(Object, 1) (Line: 64)
    Symfony\Component\HttpKernel\HttpKernel->handle(Object, 1, 1) (Line: 57)
    Drupal\Core\StackMiddleware\Session->handle(Object, 1, 1) (Line: 47)
    Drupal\Core\StackMiddleware\KernelPreHandle->handle(Object, 1, 1) (Line: 207)
    Drupal\page_cache\StackMiddleware\PageCache->fetch(Object, 1, 1) (Line: 121)
    Drupal\page_cache\StackMiddleware\PageCache->lookup(Object, 1, 1) (Line: 75)
    Drupal\page_cache\StackMiddleware\PageCache->handle(Object, 1, 1) (Line: 47)
    Drupal\Core\StackMiddleware\ReverseProxyMiddleware->handle(Object, 1, 1) (Line: 50)
    Drupal\Core\StackMiddleware\NegotiationMiddleware->handle(Object, 1, 1) (Line: 23)
    Stack\StackedHttpKernel->handle(Object, 1, 1) (Line: 656)
    Drupal\Core\DrupalKernel->handle(Object) (Line: 19)
    
  • Notice: Undefined index: from in biocodex_preprocess_page() (line 938 of themes/biocodex/biocodex.theme).
    biocodex_preprocess_page(Array, 'page', Array) (Line: 287)
    Drupal\Core\Theme\ThemeManager->render('page', Array) (Line: 435)
    Drupal\Core\Render\Renderer->doRender(Array, ) (Line: 195)
    Drupal\Core\Render\Renderer->render(Array) (Line: 490)
    Drupal\Core\Template\TwigExtension->escapeFilter(Object, Array, 'html', NULL, 1) (Line: 302)
    __TwigTemplate_ca4e890221b05d8eb544a486608af4724c44a8b112ef7a47902661d29a187ea6->doDisplay(Array, Array) (Line: 379)
    Twig_Template->displayWithErrorHandling(Array, Array) (Line: 347)
    Twig_Template->display(Array) (Line: 358)
    Twig_Template->render(Array) (Line: 64)
    twig_render_template('themes/biocodex/templates/html.html.twig', Array) (Line: 384)
    Drupal\Core\Theme\ThemeManager->render('html', Array) (Line: 435)
    Drupal\Core\Render\Renderer->doRender(Array, ) (Line: 195)
    Drupal\Core\Render\Renderer->render(Array) (Line: 147)
    Drupal\Core\Render\MainContent\HtmlRenderer->Drupal\Core\Render\MainContent\{closure}() (Line: 574)
    Drupal\Core\Render\Renderer->executeInRenderContext(Object, Object) (Line: 148)
    Drupal\Core\Render\MainContent\HtmlRenderer->renderResponse(Array, Object, Object) (Line: 90)
    Drupal\Core\EventSubscriber\MainContentViewSubscriber->onViewRenderArray(Object, 'kernel.view', Object) (Line: 111)
    Drupal\Component\EventDispatcher\ContainerAwareEventDispatcher->dispatch('kernel.view', Object) (Line: 149)
    Symfony\Component\HttpKernel\HttpKernel->handleRaw(Object, 1) (Line: 64)
    Symfony\Component\HttpKernel\HttpKernel->handle(Object, 1, 1) (Line: 57)
    Drupal\Core\StackMiddleware\Session->handle(Object, 1, 1) (Line: 47)
    Drupal\Core\StackMiddleware\KernelPreHandle->handle(Object, 1, 1) (Line: 207)
    Drupal\page_cache\StackMiddleware\PageCache->fetch(Object, 1, 1) (Line: 121)
    Drupal\page_cache\StackMiddleware\PageCache->lookup(Object, 1, 1) (Line: 75)
    Drupal\page_cache\StackMiddleware\PageCache->handle(Object, 1, 1) (Line: 47)
    Drupal\Core\StackMiddleware\ReverseProxyMiddleware->handle(Object, 1, 1) (Line: 50)
    Drupal\Core\StackMiddleware\NegotiationMiddleware->handle(Object, 1, 1) (Line: 23)
    Stack\StackedHttpKernel->handle(Object, 1, 1) (Line: 656)
    Drupal\Core\DrupalKernel->handle(Object) (Line: 19)
    
  • Notice: Undefined index: from in biocodex_preprocess_page() (line 938 of themes/biocodex/biocodex.theme).
    biocodex_preprocess_page(Array, 'page', Array) (Line: 287)
    Drupal\Core\Theme\ThemeManager->render('page', Array) (Line: 435)
    Drupal\Core\Render\Renderer->doRender(Array, ) (Line: 195)
    Drupal\Core\Render\Renderer->render(Array) (Line: 490)
    Drupal\Core\Template\TwigExtension->escapeFilter(Object, Array, 'html', NULL, 1) (Line: 302)
    __TwigTemplate_ca4e890221b05d8eb544a486608af4724c44a8b112ef7a47902661d29a187ea6->doDisplay(Array, Array) (Line: 379)
    Twig_Template->displayWithErrorHandling(Array, Array) (Line: 347)
    Twig_Template->display(Array) (Line: 358)
    Twig_Template->render(Array) (Line: 64)
    twig_render_template('themes/biocodex/templates/html.html.twig', Array) (Line: 384)
    Drupal\Core\Theme\ThemeManager->render('html', Array) (Line: 435)
    Drupal\Core\Render\Renderer->doRender(Array, ) (Line: 195)
    Drupal\Core\Render\Renderer->render(Array) (Line: 147)
    Drupal\Core\Render\MainContent\HtmlRenderer->Drupal\Core\Render\MainContent\{closure}() (Line: 574)
    Drupal\Core\Render\Renderer->executeInRenderContext(Object, Object) (Line: 148)
    Drupal\Core\Render\MainContent\HtmlRenderer->renderResponse(Array, Object, Object) (Line: 90)
    Drupal\Core\EventSubscriber\MainContentViewSubscriber->onViewRenderArray(Object, 'kernel.view', Object) (Line: 111)
    Drupal\Component\EventDispatcher\ContainerAwareEventDispatcher->dispatch('kernel.view', Object) (Line: 149)
    Symfony\Component\HttpKernel\HttpKernel->handleRaw(Object, 1) (Line: 64)
    Symfony\Component\HttpKernel\HttpKernel->handle(Object, 1, 1) (Line: 57)
    Drupal\Core\StackMiddleware\Session->handle(Object, 1, 1) (Line: 47)
    Drupal\Core\StackMiddleware\KernelPreHandle->handle(Object, 1, 1) (Line: 207)
    Drupal\page_cache\StackMiddleware\PageCache->fetch(Object, 1, 1) (Line: 121)
    Drupal\page_cache\StackMiddleware\PageCache->lookup(Object, 1, 1) (Line: 75)
    Drupal\page_cache\StackMiddleware\PageCache->handle(Object, 1, 1) (Line: 47)
    Drupal\Core\StackMiddleware\ReverseProxyMiddleware->handle(Object, 1, 1) (Line: 50)
    Drupal\Core\StackMiddleware\NegotiationMiddleware->handle(Object, 1, 1) (Line: 23)
    Stack\StackedHttpKernel->handle(Object, 1, 1) (Line: 656)
    Drupal\Core\DrupalKernel->handle(Object) (Line: 19)
    
  • Notice: Undefined index: from in biocodex_preprocess_page() (line 938 of themes/biocodex/biocodex.theme).
    biocodex_preprocess_page(Array, 'page', Array) (Line: 287)
    Drupal\Core\Theme\ThemeManager->render('page', Array) (Line: 435)
    Drupal\Core\Render\Renderer->doRender(Array, ) (Line: 195)
    Drupal\Core\Render\Renderer->render(Array) (Line: 490)
    Drupal\Core\Template\TwigExtension->escapeFilter(Object, Array, 'html', NULL, 1) (Line: 302)
    __TwigTemplate_ca4e890221b05d8eb544a486608af4724c44a8b112ef7a47902661d29a187ea6->doDisplay(Array, Array) (Line: 379)
    Twig_Template->displayWithErrorHandling(Array, Array) (Line: 347)
    Twig_Template->display(Array) (Line: 358)
    Twig_Template->render(Array) (Line: 64)
    twig_render_template('themes/biocodex/templates/html.html.twig', Array) (Line: 384)
    Drupal\Core\Theme\ThemeManager->render('html', Array) (Line: 435)
    Drupal\Core\Render\Renderer->doRender(Array, ) (Line: 195)
    Drupal\Core\Render\Renderer->render(Array) (Line: 147)
    Drupal\Core\Render\MainContent\HtmlRenderer->Drupal\Core\Render\MainContent\{closure}() (Line: 574)
    Drupal\Core\Render\Renderer->executeInRenderContext(Object, Object) (Line: 148)
    Drupal\Core\Render\MainContent\HtmlRenderer->renderResponse(Array, Object, Object) (Line: 90)
    Drupal\Core\EventSubscriber\MainContentViewSubscriber->onViewRenderArray(Object, 'kernel.view', Object) (Line: 111)
    Drupal\Component\EventDispatcher\ContainerAwareEventDispatcher->dispatch('kernel.view', Object) (Line: 149)
    Symfony\Component\HttpKernel\HttpKernel->handleRaw(Object, 1) (Line: 64)
    Symfony\Component\HttpKernel\HttpKernel->handle(Object, 1, 1) (Line: 57)
    Drupal\Core\StackMiddleware\Session->handle(Object, 1, 1) (Line: 47)
    Drupal\Core\StackMiddleware\KernelPreHandle->handle(Object, 1, 1) (Line: 207)
    Drupal\page_cache\StackMiddleware\PageCache->fetch(Object, 1, 1) (Line: 121)
    Drupal\page_cache\StackMiddleware\PageCache->lookup(Object, 1, 1) (Line: 75)
    Drupal\page_cache\StackMiddleware\PageCache->handle(Object, 1, 1) (Line: 47)
    Drupal\Core\StackMiddleware\ReverseProxyMiddleware->handle(Object, 1, 1) (Line: 50)
    Drupal\Core\StackMiddleware\NegotiationMiddleware->handle(Object, 1, 1) (Line: 23)
    Stack\StackedHttpKernel->handle(Object, 1, 1) (Line: 656)
    Drupal\Core\DrupalKernel->handle(Object) (Line: 19)
    
  • Notice: Undefined index: from in biocodex_preprocess_page() (line 938 of themes/biocodex/biocodex.theme).
    biocodex_preprocess_page(Array, 'page', Array) (Line: 287)
    Drupal\Core\Theme\ThemeManager->render('page', Array) (Line: 435)
    Drupal\Core\Render\Renderer->doRender(Array, ) (Line: 195)
    Drupal\Core\Render\Renderer->render(Array) (Line: 490)
    Drupal\Core\Template\TwigExtension->escapeFilter(Object, Array, 'html', NULL, 1) (Line: 302)
    __TwigTemplate_ca4e890221b05d8eb544a486608af4724c44a8b112ef7a47902661d29a187ea6->doDisplay(Array, Array) (Line: 379)
    Twig_Template->displayWithErrorHandling(Array, Array) (Line: 347)
    Twig_Template->display(Array) (Line: 358)
    Twig_Template->render(Array) (Line: 64)
    twig_render_template('themes/biocodex/templates/html.html.twig', Array) (Line: 384)
    Drupal\Core\Theme\ThemeManager->render('html', Array) (Line: 435)
    Drupal\Core\Render\Renderer->doRender(Array, ) (Line: 195)
    Drupal\Core\Render\Renderer->render(Array) (Line: 147)
    Drupal\Core\Render\MainContent\HtmlRenderer->Drupal\Core\Render\MainContent\{closure}() (Line: 574)
    Drupal\Core\Render\Renderer->executeInRenderContext(Object, Object) (Line: 148)
    Drupal\Core\Render\MainContent\HtmlRenderer->renderResponse(Array, Object, Object) (Line: 90)
    Drupal\Core\EventSubscriber\MainContentViewSubscriber->onViewRenderArray(Object, 'kernel.view', Object) (Line: 111)
    Drupal\Component\EventDispatcher\ContainerAwareEventDispatcher->dispatch('kernel.view', Object) (Line: 149)
    Symfony\Component\HttpKernel\HttpKernel->handleRaw(Object, 1) (Line: 64)
    Symfony\Component\HttpKernel\HttpKernel->handle(Object, 1, 1) (Line: 57)
    Drupal\Core\StackMiddleware\Session->handle(Object, 1, 1) (Line: 47)
    Drupal\Core\StackMiddleware\KernelPreHandle->handle(Object, 1, 1) (Line: 207)
    Drupal\page_cache\StackMiddleware\PageCache->fetch(Object, 1, 1) (Line: 121)
    Drupal\page_cache\StackMiddleware\PageCache->lookup(Object, 1, 1) (Line: 75)
    Drupal\page_cache\StackMiddleware\PageCache->handle(Object, 1, 1) (Line: 47)
    Drupal\Core\StackMiddleware\ReverseProxyMiddleware->handle(Object, 1, 1) (Line: 50)
    Drupal\Core\StackMiddleware\NegotiationMiddleware->handle(Object, 1, 1) (Line: 23)
    Stack\StackedHttpKernel->handle(Object, 1, 1) (Line: 656)
    Drupal\Core\DrupalKernel->handle(Object) (Line: 19)
    
  • Notice: Undefined variable: nid in biocodex_preprocess_page() (line 983 of themes/biocodex/biocodex.theme).
    biocodex_preprocess_page(Array, 'page', Array) (Line: 287)
    Drupal\Core\Theme\ThemeManager->render('page', Array) (Line: 435)
    Drupal\Core\Render\Renderer->doRender(Array, ) (Line: 195)
    Drupal\Core\Render\Renderer->render(Array) (Line: 490)
    Drupal\Core\Template\TwigExtension->escapeFilter(Object, Array, 'html', NULL, 1) (Line: 302)
    __TwigTemplate_ca4e890221b05d8eb544a486608af4724c44a8b112ef7a47902661d29a187ea6->doDisplay(Array, Array) (Line: 379)
    Twig_Template->displayWithErrorHandling(Array, Array) (Line: 347)
    Twig_Template->display(Array) (Line: 358)
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Diarrhée du voyageur

Traitement prophylactique de la diarrhée du voyageur : impact du renforcement du microbiote intestinal ? Quelques études le suggèrent, même si elles sont encore peu nombreuses.

Les personnes qui voyagent dans des pays au climat chaud et aux conditions d'hygiène précaires sont exposées à des risques importants de diarrhées infectieuses : entre 10% et 40% d'entre elles seraient touchées durant leur séjour1. Dans la plupart des cas, ces diarrhées sont dues à des bactéries pathogènes (Escherichia coli, Salmonella, Shigella, Campylobacter jejuni...). Mais des parasites (Giardia lamblia, Cyclospora, Cryptosporidium...) et des virus (norovirus, rotavirus...) sont impliqués dans environ 10% des cas2.

Un trouble pas toujours anecdotique

Or, si la « tourista » est fréquente, elle n'est pas pour autant sans conséquences. En effet, la diarrhée perturbe au moins temporairement l'équilibre du microbiote intestinal, ce qui pourrait avoir des conséquences à long terme, en augmentant notamment le risque de développer un syndrome de l'intestin irritable3. À court terme, elle s’accompagne d’un risque de perturbation de l’absorption de médicaments, et de déshydratation dangereuse pour les personnes fragiles.

Des probiotiques en prévention

Le microbiote étant en première ligne pour défendre l'organisme des infections entériques, l’utilisation de probiotiques est depuis longtemps envisagée en prévention de la diarrhée du voyageur. Une équipe autrichienne a par exemple réalisé, il y a près de trente ans déjà, deux études randomisées contrôlées sur les effets de la levure probiotique Saccharomyces boulardii.

Une efficacité prouvée par des études cliniques 

Plusieurs études ont montré qu’un traitement préventif avec la levure probiotique Saccharomyces boulardii permet de réduire le risque de développer une diarrhée.4,5 Quelques essais contrôlés et randomisés ont également suggéré le potentiel préventif d’associations de lactobacilles avec d’autres familles de bactéries6. Cependant, les études de bonne qualité, menées avec des prébiotiques ou des probiotiques, restent aujourd'hui encore peu nombreuses1.

Sources
1- Steffen R et al. Traveler’s diarrhea: a clinical review. JAMA 2015 ; 313 : 71-80. https://www.ncbi.nlm.nih.gov/pubmed/?term=Steffen+R%2C+Hill+DR%2C+DuPont+HL.+Traveler%E2%80%99s+diarrhea%3A+a+clinical+review.+JAMA+2015+%3B+313+%3A+71-80.
2-  CHU Rouen. La diarrhée du voyageur [en ligne]. Extrait et inspiré de « Vacinnation : visa pour... la diarrhée du voyageur. Aspects actuels et perspectives ». Dr Patrice Bourée – N°8/1997. Mis à jour le 13 août 1998 par Jean Philippe Leroy. [consulté le 30/01/2017]. Disponible à l'adresse : http://www.chu-rouen.fr/cap/tourista.html
3- Schwille-Kiuntke J et al. Systematic review and meta-analysis: post-infectious irritable bowel syndrome after traveller’s diarrhoea. Aliment Pharmacol Ther 2015 ; 41 : 1029-37. https://www.ncbi.nlm.nih.gov/pubmed/25871571
4- Kollaritsch H et al. Prevention of traveller’s diarrhea : comparaison of different non antibiotic preparations. Travel Med Int 1989 : 9-17. https://www.optibacprobiotics.co.uk/uploads/kollaritsch,_h._et_al_(1993)_prevention_of_traveller's_diarrhoea_for_travelling_abroad_optibac_probiotics_www.optibacprobiotics.co.uk.pdf
5- Kollaritsch H et al. [Prevention of traveler’s diarrhea with Saccharomyces boulardii. Results of a placebo controlled double-blind study]. Fortschr Med 1993 ; 111 : 152-6. https://www.ncbi.nlm.nih.gov/pubmed/8486328
6- McFarland LV. Meta-analysis of probiotics for the prevention of traveler’s diarrhea. Travel Med Infect Dis. 2007;5(2):97-105. https://www.ncbi.nlm.nih.gov/pubmed/?term=McFarland+LV.+Meta-analysis+of+probiotics+for+the+prevention+of+traveler%E2%80%99s+diarrhea.+Travel+Med+Infect+Dis.+2007%3B5(2)%3A97-105.

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Le BMI en bref

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