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Vaccination after antibiotic therapy: effect on immunity and role of the microbiota

In individuals with low pre-vaccination immunity against influenza*, taking antibiotics leads to gut dysbiosis which disrupts the immune response to the flu vaccine. A team of scientists tried to find out why.   Several studies have documented the pivotal role of the gut microbiota in imm...
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Cancer immunotherapy: no prior antibiotic treatment

Gut dysbiosis caused by the prior use of broad-spectrum antibiotics could impact the efficacy of cancer immunotherapy, in turn leading to a decrease in overall patient survival.   Immune checkpoint inhibitor (ICI) therapy is a form of immunotherapy that provides a new therapeutic option a...
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Lantibiotics: a new avenue in the fight against resistant bacteria

Colonization of the gastrointestinal tract by a strain of vancomycin-resistant Enterococcus faecium could largely be reduced by the administration of bacteria that naturally synthesize an effective and selective lantibiotic*.   How can we fight against the transmission of pathogens highly...
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Antibiotic-associated diarrhea

Antibiotics, by disturbing the intestinal microbiota, can cause more-or-less severe diarrhea.
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