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Obesity: fecal virome transplant on trial

Due to their antagonistic properties, bacteriophages have the potential to modulate the intestinal microbiota. One study has shown that virome transplantation can make the phenotype of obese recipient mice closely resemble that of lean donor mice.   In recent years, the link between gut d...
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Involvement of E. faecalis in alcoholic hepatitis

The gut bacterium E. faecalis migrates to the liver in the presence of alcohol and can produce a toxin that aggravates alcoholic hepatitis. A bacteriophage specifically targeting this bacterium eliminates inflammation and hepatic lesions.   Alcoholic hepatitis is the most severe form of a...
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Fecal transplant and recurrent Clostridium difficile infections: bacteriophages are necessary in donors

According to a Canadian study, the diversity and relative abundance in donors’ bacteriophages seem to have an impact on the success of fecal transplants in patients with recurrent Clostridium difficile infections.   Despite the positive results obtained with fecal microbiota transplants (...
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