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Could the metabolome be used to better diagnose c. Difficile infections?

Two large families of metabolites (the first are derived from leucine and the second from bile acids) could have the potential to discriminate between a C. difficile infection and an asymptomatic C. difficile colonization.   Clostridioides difficile* infection (CDI) affects about 450,000 ...
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Fecal transplant and recurrent Clostridium difficile infections: bacteriophages are necessary in donors

According to a Canadian study, the diversity and relative abundance in donors’ bacteriophages seem to have an impact on the success of fecal transplants in patients with recurrent Clostridium difficile infections.   Despite the positive results obtained with fecal microbiota transplants (...
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C. difficile infection: studying the role of the virome

Fecal transplant is a known treatment for Clostridium difficile (CD) infections, especially for antibiotic-resistant cases, with a success rate of almost 90%. During the transfer of the fecal microbiota, it is not only the bacterial microbiota from a healthy subject that is implanted in the recipien...
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