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Early dysbiosis in Crohn’s disease, delayed dysbiosis in ulcerative colitis

An international team has advanced a hypothesis on the etiology of chronic inflammatory bowel diseases (CIBD): neonatal intestinal dysbiosis is thought to induce the development of Crohn’s disease, while ulcerative colitis is thought to be correlated with day-to-day disruptions of the microbiota. ...
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CIBD: a promising therapy to protect the mucus layer

A western diet significantly modifies the mucosa of the host's colon, in particular the mucus layer. In an animal model, ingestion of fiber and of a strain of Bifidobacterium is thought to help compensate for its effects. This issue warrants close monitoring in the case of Chronic Inflammatory Bowel...
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A role for bacterial urease in Crohn’s disease

Urease serves as a nitrogen source provider for amino acid synthesis and thus for bacterial growth. It is associated with gut dysbiosis during chronic inflammatory bowel disease.   Bacterial urease plays the role of substrate in the bacterial production of amino acids by serving as a nitr...
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IBD

Chronic inflammatory bowel diseases (IBDs), like Crohn’s disease and ulcerative colitis, are correlated with an imbalance in the microbiota.
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