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A role for bacterial urease in Crohn’s disease

Urease serves as a nitrogen source provider for amino acid synthesis and thus for bacterial growth. It is associated with gut dysbiosis during chronic inflammatory bowel disease.   Bacterial urease plays the role of substrate in the bacterial production of amino acids by serving as a nitr...
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The role of duodenal microbiota in ulcerative colitis

In children with ulcerative colitis, the duodenal microbiota shows significant anomalies that suggest it is involved in colon inflammation.   Intestinal dysbioses are associated with chronic inflammatory bowel disease (CIBD). Until now, data was only available regarding the microbiota of ...
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Specific dysbiosis characterizes CIBD-related colon cancer

The disruptions in the intestinal microbiota associated with colon cancer are not all the same, depending on whether or not the cancer is related to a chronic inflammatory bowel disease.   Among the 43,000 cases of colon cancer diagnosed every year in France, 0.4% are related to chronic i...
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IBD

Chronic inflammatory bowel diseases (IBDs), like Crohn’s disease and ulcerative colitis, are correlated with an imbalance in the microbiota.
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