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Hepatic encephalopathy: oral fecal microbiota transplant shows good tolerability

A phase 1 clinical trial showed that oral fecal microbiota capsules were well tolerated by patients with cirrhosis and prone to developing hepatic encephalopathy.   Hepatic encephalopathy (HE) is a complication of liver failure and symptoms include more or less severe, sometimes irreversi...
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Gut fungal dysbiosis: what role in cirrhosis?

The gut mycobiota is believed to be involved in the development of cirrhosis and its complications, and as such should be considered when making therapeutic choices. A bacteria/fungi ratio could even be used as a predictor for the risk of hospitalization.   As their immune system is weake...
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Should the use of PPI be limited in advanced cirrhosis?

Taking a PPI is thought to promote colonization of the intestinal microbiota by bacteria from the oral cavity. This dysbiosis is associated with an increased risk of complications and rehospitalization in patients presenting with advanced cirrhosis, according to an American study.   By re...
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