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Metformin and gut microbiota: a complex relationship

Recent studies suggest that metformin’s therapeutic effects could be partly related to its interaction with the gut microbiota. The same could also be true of its gastrointestinal adverse effects.   Gastrointestinal adverse events (GIAEs) are frequently reported in patients with type 2 di...
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The oral microbiota as a biomarker for metabolic syndrome

The definition of metabolic syndrome does not always meet with general agreement, but its association with low-grade inflammation, its cardiovascular consequences and the risk of type 2 diabetes mellitus are real. Korean researchers have tried to determine whether the oral microbiota might contain b...
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TMAO and cardiovascular risk in type 2 diabetes mellitus with chronic kidney disease renal failure

In patients with type 2 diabetes mellitus and chronic kidney disease, dysbiosis in the intestinal microbiota causes an increase in serum levels of trimethylamine-N-oxide (TMAO), a cardiovascular risk factor.   TMAO is naturally produced from TMA (trimethylamine) when intestinal bacteria b...
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Nutritional modulation

The composition of intestinal microbiota depends on what food is ingested and has consequences on overall metabolism. Intestinal microbiota starts developing at birth, and its composition is influenced by what we eat. Food intake can therefore play a role – good or bad – in the modulation of inte...
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Metabolic syndrome

The presence of cardiovascular and metabolic risk factors, like elevated glycemia and cholesterol, hypertension, … is influenced by the composition of the intestinal microbiota.
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