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TMAO and cardiovascular risk in type 2 diabetes mellitus with chronic kidney disease renal failure

In patients with type 2 diabetes mellitus and chronic kidney disease, dysbiosis in the intestinal microbiota causes an increase in serum levels of trimethylamine-N-oxide (TMAO), a cardiovascular risk factor.   TMAO is naturally produced from TMA (trimethylamine) when intestinal bacteria b...
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Type 2 diabetes: treatment resistance due to microbiota

A new kind of treatment has been in use for several years for people with type 2 diabetes: GLP-1 analogues (glucagon-like peptide 1), which stimulate insulin secretion via the gut-brain axis. These medications offer many advantages (weight loss, low risk of hypoglycemia, etc.). However, not all pati...
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Nutritional modulation

The composition of intestinal microbiota depends on what food is ingested and has consequences on overall metabolism. Intestinal microbiota starts developing at birth, and its composition is influenced by what we eat. Food intake can therefore play a role – good or bad – in the modulation of inte...
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Metabolic syndrome

The presence of cardiovascular and metabolic risk factors, like elevated glycemia and cholesterol, hypertension, … is influenced by the composition of the intestinal microbiota.
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