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Microbiota transplant and type 1 diabetes mellitus: a trial in humans

Fecal microbiota transplantation is accompanied by changes in microbial metabolites and T cells involved in autoimmunity and may preserve residual function of pancreatic β-cells in type 1 diabetes mellitus.   Type 1 diabetes mellitus (T1DM) is an autoimmune disease that leads to the destr...

Kidney transplant: is pre-operative dysbiosis a risk factor for diabetes?

Patients affected by kidney failure who develop diabetes following a transplant may have been suffering from a pre-operative gut dysbiosis, the precise details of which have not yet been determined.   Patients affected by kidney failure often suffer from severe metabolic disorders. Diabet...

Metformin and gut microbiota: a complex relationship

Recent studies suggest that metformin’s therapeutic effects could be partly related to its interaction with the gut microbiota. The same could also be true of its gastrointestinal adverse effects.   Gastrointestinal adverse events (GIAEs) are frequently reported in patients with type 2 di...
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Nutritional modulation

The composition of intestinal microbiota depends on what food is ingested and has consequences on overall metabolism. Intestinal microbiota starts developing at birth, and its composition is influenced by what we eat. Food intake can therefore play a role – good or bad – in the modulation of inte...

Metabolic syndrome

The presence of cardiovascular and metabolic risk factors, like elevated glycemia and cholesterol, hypertension, … is influenced by the composition of the intestinal microbiota.
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