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Could the metabolome be used to better diagnose c. Difficile infections?

Two large families of metabolites (the first are derived from leucine and the second from bile acids) could have the potential to discriminate between a C. difficile infection and an asymptomatic C. difficile colonization.   Clostridioides difficile* infection (CDI) affects about 450,000 ...
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The intestinal microbiota could increase rotavirus vaccine effectiveness

Preliminary results suggest that targeted changes in the intestinal microbiota could improve rotavirus vaccine immunogenicity, which is decreasing in developing countries where prevalence of this disease is highest.   Rotavirus vaccination, although effective in Western countries, is much...
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Role of the intestinal microbiota in diarrhea after kidney transplant

Intestinal dysbiosis is thought to be at the root of diarrhea in kidney transplant recipients. This is an important finding to consider to improve diagnosis and management.   In the year following their kidney transplant, patients may suffer from diarrhea which impairs their quality of li...
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IBD

Chronic inflammatory bowel diseases (IBDs), like Crohn’s disease and ulcerative colitis, are correlated with an imbalance in the microbiota.
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Infectious diarrhea

The intestinal equilibrium is significantly affected in cases of infectious diarrhea. Studying the microbial ecosystem over the course of the infection has resulted in notable progress in the treatment of this disorder.
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