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Breast cancer: efficacy of immunotherapy conditioned by the gut microbiota?

A recent study published in Cancer Research suggests that the gut microbiota affects responses to immunotherapy in HER2-positive breast cancer. How so? Via local and systemic modulation of the immune system.   Trastuzumab is the first therapeutic option for women with HER2-positive breast...
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Melanoma: fecal microbiota transplant to overcome resistance to anti–pd-1?

A recent study published in Science shows that modulating the gut microbiota helps advanced melanoma patients respond to anti-PD-1 immunotherapy which their tumors had previously resisted. How? Thanks to fecal microbiota transplantation (FMT). Anti-PD-1 has been one of the major therapeutic advan...
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Can fecal transplantation restore the microbiota of Caesarean-born infants?

A new study published in Cell shows that the gut microbiota of infants born by Caesarean section can be restored through a fecal microbiota transplant from their mothers. The result is a gut microbiota resembling that of vaginally born infants.   The gut microbiota of infants born by Caes...
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