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HIV-1: persistent post-infection bacterial and viral gut dysbiosis

People recently infected with HIV-1 develop changes in their viral and bacterial gut populations. This pronounced dysbiosis, unresolved by antiretroviral therapy, persists during the chronic phase of the disease.   Lymphoid and epithelial tissues of the digestive tube are damaged followin...
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The intestinal microbiota may influence aids resistance

HIV “elite” or “natural” controllers are HIV-positive patients who, without treatment, still do not develop AIDS. A Spanish-Swedish study revealed significant differences in the composition of their intestinal microbiota.   In the vast majority of cases, untreated HIV infection leads to A...
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HIV: the vaginal flora affects the effectiveness of a preventative treatment

The composition of the vaginal microbiota influences how effective a topical tenofovir treatment is in preventing HIV infection in women. So say researchers who analyzed the impact of the vaginal microbiota on the response to this treatment, whose effectiveness can vary between 0 and 40% according t...
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