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How does the gut microbiota remotely control the thymus?

The gut microbiota seems to remotely control the multiplication and maturation of some T cells in the thymus, through microbial metabolites. In return, T cells seem to have an impact on the homeostasis of the gut barrier.   How does the gut microbiota modulate immune functions? This quest...
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HIV-1: persistent post-infection bacterial and viral gut dysbiosis

People recently infected with HIV-1 develop changes in their viral and bacterial gut populations. This pronounced dysbiosis, unresolved by antiretroviral therapy, persists during the chronic phase of the disease.   Lymphoid and epithelial tissues of the digestive tube are damaged followin...
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Childhood immune system: the benefits of vaginal delivery

Vaginal delivery promotes the transmission of maternal microbiota, whose composition is involved in the development of newborns’ immune system, especially through the lipopolysaccharide biosynthesis pathway.   19.1% of deliveries worldwide are performed by C-section. This number rises to ...
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