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HIV-1: persistent post-infection bacterial and viral gut dysbiosis

People recently infected with HIV-1 develop changes in their viral and bacterial gut populations. This pronounced dysbiosis, unresolved by antiretroviral therapy, persists during the chronic phase of the disease.   Lymphoid and epithelial tissues of the digestive tube are damaged followin...
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Childhood immune system: the benefits of vaginal delivery

Vaginal delivery promotes the transmission of maternal microbiota, whose composition is involved in the development of newborns’ immune system, especially through the lipopolysaccharide biosynthesis pathway.   19.1% of deliveries worldwide are performed by C-section. This number rises to ...
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The intestinal microbiota may influence aids resistance

HIV “elite” or “natural” controllers are HIV-positive patients who, without treatment, still do not develop AIDS. A Spanish-Swedish study revealed significant differences in the composition of their intestinal microbiota.   In the vast majority of cases, untreated HIV infection leads to A...
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