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Breast cancer: efficacy of immunotherapy conditioned by the gut microbiota?

A recent study published in Cancer Research suggests that the gut microbiota affects responses to immunotherapy in HER2-positive breast cancer. How so? Via local and systemic modulation of the immune system.   Trastuzumab is the first therapeutic option for women with HER2-positive breast...
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Melanoma: fecal microbiota transplant to overcome resistance to anti–pd-1?

A recent study published in Science shows that modulating the gut microbiota helps advanced melanoma patients respond to anti-PD-1 immunotherapy which their tumors had previously resisted. How? Thanks to fecal microbiota transplantation (FMT). Anti-PD-1 has been one of the major therapeutic advan...
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Bacteria that deliver treatment to the heart of the tumor

Release molecules directly in the heart of the tumor to assist the immune response and facilitate regression: this is the challenge taken up by probiotic bacteria specially designed to reach their target, multiply and release their cellular content.   While immune checkpoint inhibitors (I...
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