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Vaccination after antibiotic therapy: effect on immunity and role of the microbiota

In individuals with low pre-vaccination immunity against influenza*, taking antibiotics leads to gut dysbiosis which disrupts the immune response to the flu vaccine. A team of scientists tried to find out why.   Several studies have documented the pivotal role of the gut microbiota in imm...
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The intestinal microbiota could increase rotavirus vaccine effectiveness

Preliminary results suggest that targeted changes in the intestinal microbiota could improve rotavirus vaccine immunogenicity, which is decreasing in developing countries where prevalence of this disease is highest.   Rotavirus vaccination, although effective in Western countries, is much...
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Will there be microorganism-based vaccines in the future?

Commensal flora not only protects mucosa from pathogens but it also modulates the quality and quantity of systemic innate and adaptive immune responses. As a result, could it be the basis for preventative and even therapeutic vaccines? This is the question asked by an American researcher in the revi...
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