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Gastroenterology

The Janus face of Antibiotics: Life Savers and Microbiota Disruptors

Drug
Dermatology Gynecology Pulmonology Pediatrics Otorhinolaryngology Gastroenterology

From 18 to 24 November, the WHO will be running World Antibiotic Awareness Week (WAAW). WAAW reminds us that although antibiotics were one of the major therapeutic advances of the 20th century, they can also have an adverse impact on the various microbiota and cause antibiotic resistance.1

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About this article

Created 20 November 2020
Updated 04 March 2022

From the antibiotic era to the microbiota era

As an expert on microbiota, the Biocodex Microbiota Institute will participate in this event by dedicating a special edition to the impact of antibiotics on the body’s microbiota:

- Gut microbiota: up to 35% of patients using antibiotics suffer from diarrhea2,3,4 

- Urogenital microbiota: 10% to 30% of women develop vulvovaginal candidiasis following treatment with antibiotics5 

- Skin microbiota: 60% of patients treated for acne show macrolide-resistant strains of Cutibacterium acnes 

- ENT microbiota: antibiotics administered to treat upper respiratory tract infections increase the incidence of acute otitis media by a factor 2.6 

- Lung microbiota: broad-spectrum antibiotics used to treat pulmonary infections play a central role in the emergence of antibiotic resistance

 

Special thematic paper

This 12-page issue presents the key points based on scientific data, expert opinions, and clinical cases.

Discover it
and download it!
Sources

1. https://www.who.int/news-room/events/detail/2020/11/18/default-calendar/world-antimicrobial-awareness-week-2020

2. McFarland LV, Ozen M, Dinleyici EC et al. Comparison of pediatric and adult antibiotic-associated diarrhea and Clostridium difficile infections. World J Gastroenterol. 2016 Mar 21;22(11):3078-104.

3. Bartlett JG. Clinical practice. Antibiotic-associated diarrhea. N Engl J Med 2002;346:334-9.

4. Theriot CM, Young VB. Interactions Between the Gastrointestinal Microbiome and Clostridium difficile. Annu Rev Microbiol. 2015;69:445-461.

5. Shukla A, Sobel JD. Vulvovaginitis Caused by Candida Species Following Antibiotic Exposure. Curr Infect Dis Rep. 2019 Nov 9;21(11):44.

Tags
AAD C Difficile Atopic dermatitis Otitis Asthma Diarrhea Antibiotic Antibiotic resistance Dysbiosis

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    Created 20 November 2020
    Updated 04 March 2022

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