Dear Readers, this newsletter highlights some of the articles in this edition, written by experts in the field, which should arouse your curiosity. Our decision to focus on the scientific area of Microbiotas (with a “M” and a “s”) was motivated by the exponential rise in the number of discoveries and articles illustrating the importance of the relationships we have from birth with our microbiotas (gut, gastric, urologic, pulmonary…).
Individually, we do not all have the same risk of liver diseases. Only a small proportion of individuals, with equivalent alcohol consumption and comparable excess weight, develop hepatitis, cirrhosis or hepatocellular carcinoma.
In this edition, Dr. Anne-Marie Cassard and Prof. Gabriel Perlemuter (Clamart, France) describe how the gut microbiota has emerged as a key cofactor in the appearance of nutritional liver diseases; alcoholic liver disease (ALD) related to alcohol consumption and metabolic steatosis related to excess weight, also known as non-alcoholic fatty liver disease (NAFLD).
Data on the role of gut microbiota in aging processes are limited. In this edition, Prof. Harry Sokol (Paris, France) comments on recent work by Han et al. showing how some bacterial genes may be involved in life expectancy.
The gastrointestinal symptoms reported in children with autism have indicated an influence of microbiota on the pathophysiology of the disease. Prof. Emmanuel Mas (Toulouse, France) describes the promising results obtained by Kang et al. on digestive and behavioural disorders in children with autism following faecal microbiota transplantation.
the literature review of Prof. Dinleyici (Eskisehir, Turkey), the resistance to chemotherapy induced by Fusobacterium nucleatum in colon cancer, the potential value of some probiotics in treating liver diseases, and the fact that the gut microbiota could be used as a diagnostic marker in certain digestive disorders are discussed.
Finally, Prof. Zakharenko (Moscow, Russia) presents his scientific selection from the NeuroGASTRO meeting organized by the European Society of Neurogastroenterology and Motility (24–26 August 2017; Cork, Ireland).