Skip to main content
About the Institute
  • English
  • Français
  • Español
  • Russian
  • Portuguese

Breadcrumb

  1. Home
  2. Urinary microbiota in continent women: the effect of age
  • Our publications
    • News
    • Microbiota Mag
    • Thematic folders
    • Overviews - Microbiota Magazine
  • About the Institute
    • Partnerships
    • Press room
  • Congresses
    • Congress calendar
    • Congress reviews
  • Continuing Medical Education
    • Accrediting courses
    • Xpeer App
  • Useful documents
    • Infographics
    About the Institute

    Join the microbiota community

    • Facebook
    • Twitter
    • LinkedIn
    • YouTube

Lay public section

Find here your dedicated section
Gastroenterology
Gynecology
Pediatrics
Dermatology

Breadcrumb

  1. Home
  2. Urinary microbiota in continent women: the effect of age

Urinary microbiota in continent women: the effect of age

Incontinence
Urology

The composition of the urinary microbiota in continent adult women varies according to age, possibly due to the influence of hormones. Although certain urotypes seem to be emerging, the potential consequences are not yet understood.

Gastroenterology
Gynecology
Pediatrics
Dermatology
  • Our publications
    • News
    • Microbiota Mag
    • Thematic folders
    • Overviews - Microbiota Magazine
  • About the Institute
    • Partnerships
    • Press room
  • Congresses
    • Congress calendar
    • Congress reviews
  • Continuing Medical Education
    • Accrediting courses
    • Xpeer App
  • Useful documents
    • Infographics
    About the Institute

    Join the microbiota community

    • Facebook
    • Twitter
    • LinkedIn
    • YouTube

Lay public section

Find here your dedicated section

Sources

This article is based on scientific information

Sharing is caring

Your colleagues might be interested in this topic. Why not share it?

  • Facebook
  • Twitter
  • Mail
Photo : Urinary microbiota in continent women: the effect of age

About this article

Created 30 April 2020
Updated 31 March 2022

The bladder is not a sterile environment and the recent discovery of the urinary microbiota has opened up a whole new field of research. In this light, a cross-sectional study was carried out on 224 continent adult female patients at a large medical center in the United States, who were aged 48 years on average and were mostly Caucasian (66%) and overweight (average (sidenote: Body Mass Index.  Ratio of weight in kg to square of height in sq.m ) of 29.96 kg/m2). The subjects underwent a physical examination for a potential prolapse and were asked to fill in a questionnaire (overactive bladder, quality of life, weight, age, etc.). A urine sample taken by catheter was used to characterize their urinary microbiota.

Two methods of choice

Three methods of analysis were compared: the standard method, the expanded quantitative urine culture, or EQUC protocol (larger volume of urine, incubation under various conditions, extended incubation period) and RNA sequencing. With the standard method, bacteria were detected in 13 samples (6%), with the EQUC protocol in 115 (51%), and with RNA sequencing in 141 (63%), of which 89 were shared with the EQUC method. Therefore, the EQUC protocol and/or RNA sequencing appear to be the methods of choice, whereas the standard method is not recommended due to the high percentage of false negatives it produces.

Different urotypes

The results show that the microbiota in the bladder is variable, permitting the definition of urotypes based on the predominance (> 50%) of a taxon. The most common urotype was that dominated by Lactobacillus (19%), with no differences due to age, menopausal status, parity, sexual relations or even ethnicity (although the vaginal microbiota of black women is known to be more frequently dominated by lactobacilli). This was followed by the Streptococcus, mixed (no single taxon dominating), Gardnerella and Escherichia urotypes. The Gardnerella urotype was more common in younger women (average age of 36) and Escherichia in older women (average age of 60). The mixed urotype was frequently found in African American women (46%).

Causes and consequences?

Hormones may explain these differences in urotype, especially since they are known to have a beneficial effect on the growth of Lactobacillus in the vagina and lower urinary tract. However, the biological consequences remain a mystery. The different urotypes may provide protection from or result in a predisposition to various urinary disorders, including incontinence, overactivity or infections. In any case, the experts insist that medical treatment should preserve or restore the native urinary microbiota, particularly lactobacilli, as the disruption of this microbial community may increase susceptibility to infection.

Sources

Price TK, Hilt EE, Thomas-White K, et al. The urobiome of continent adult women: a cross-sectional study. BJOG. 2020 Jan;127(2):193-201.

Tags
Infection Menopause Bladder Urine Woman Continence Urinary disorder

en_view en_sources

    Created 30 April 2020
    Updated 31 March 2022

    About this article

    To know more about this topic.

    Main topic

    Incontinence

    Medical practice

    Urology

    Content type

    News

    Continue reading

    News
    23.01.2023

    Idiopathic urethritis in men: new infectious etiologies?

    Read the article
    23.11.2022

    Is gut dysbiosis a risk factor for HIV infection?

    Read the article

    The interaction between the oral microbiota and SARS-COV-2 infection

    Overview By Dr. Jay PatelUsher Institute of Population Health Sciences and Informatics, University of Edin...

    Find out more
    De la dysbiose intestinale à l’infection urinaire
    22.07.2022

    From gut dysbiosis to urinary tract infection

    Read the article
    18.07.2022

    The urinary microbiota: towards a new prognostic tool for prostate cancer?

    Read the article
    Photo: Postménopause : l'action bénéfique de l'estradiol sur le microbiote vaginal
    22.06.2022

    Postmenopause: the beneficial action of estradiol on the vaginal microbiota

    Read the article

    Urinary tract infections

    Infections of the lower urogenital tract are extremely common amongst women: seven out of ten women will su...

    Find out more
    VIH-1 : une dysbiose intestinale bactérienne et virale persiste post infection
    30.07.2019

    HIV-1: persistent post-infection bacterial and viral gut dysbiosis

    Read the article
    What's worth reading about microbiota
    Follow us on Twitter
    Read our thematic folder
    The Janus face of Antibiotics: Life Savers & Microbiota Disrupters
    NL13_cover
    Check out latest newsletter
    IBS, Microbiota & Covid-19
    • Our publications
      • News
      • Microbiota Mag
      • Thematic folders
      • Overviews - Microbiota Magazine
    • About the Institute
      • Partnerships
      • Press room
    • Congresses
      • Congress calendar
      • Congress reviews
    • Continuing Medical Education
      • Accrediting courses
      • Xpeer App
    • Useful documents
      • Infographics
      About the Institute

      Join the microbiota community

      • Facebook
      • Twitter
      • LinkedIn
      • YouTube

    Lay public section

    Find here your dedicated section
    Gastroenterology
    Gynecology
    Pediatrics
    Dermatology
    • English
    • Français
    • Español
    • Russian
    • Portuguese

    Browse the site

    • Our publications
      • News
      • Microbiota Mag
      • Thematic folders
      • Overviews - Microbiota Magazine
    • About the Institute
      • Partnerships
      • Press room
    • Congresses
      • Congress calendar
      • Congress reviews
    • Continuing Medical Education
      • Accrediting courses
      • Xpeer App
    • Useful documents
      • Infographics
      About the Institute

      Join the microbiota community

      • Facebook
      • Twitter
      • LinkedIn
      • YouTube

    Lay public section

    Find here your dedicated section

    Discover

    Gastroenterology
    Gynecology
    Pediatrics
    Dermatology

    Join the microbiota community

    • Facebook
    • Twitter
    • LinkedIn
    • YouTube

    Lay public section

    Find here your dedicated section

    Redirection

    You are about to be redirected and leave our website

    • Be redirected
    • Stay on the Biocodex Microbiota Institute's website

    Stay with us !

    Join the Microbiota Community of HCPs and researchers and receive “Microbiota Digest” and "Microbiota Mag" to stay up to date on the latest news about microbiota.

    * Mandatory Fields

    BMI 20-35

    Explore

    23.01.2023

    Idiopathic urethritis in men: new infectious etiologies?

    Read the article

    Impact of beer and non alcoholic comsumption on the gut microbiota

    By Pr. Bernd SchnablDivision of Gastroenterology, San Diego Digestive Diseases Research Center (SDDRC), UC ...

    Find out more

    Skin Microbiota #17

    By Pr. Satu PekkalaAcademy of Finland Research Fellow, Faculty of Sport and Health Sciences, University of ...

    Find out more

    Stay updated

    Join the Microbiota Community of HCPs and researchers and receive “Microbiota Digest” and "Microbiota Mag" to stay up to date on the latest news about microbiota.

    * Mandatory Fields

    BMI 20-35

    • Our publications
      • News
      • Microbiota Mag
      • Thematic folders
      • Overviews - Microbiota Magazine
    • About the Institute
      • Partnerships
      • Press room
    • Congresses
      • Congress calendar
      • Congress reviews
    • Continuing Medical Education
      • Accrediting courses
      • Xpeer App
    • Useful documents
      • Infographics
      About the Institute

      Join the microbiota community

      • Facebook
      • Twitter
      • LinkedIn
      • YouTube

    Lay public section

    Find here your dedicated section

    Discover

    Gastroenterology
    Gynecology
    Pediatrics
    Dermatology

    Lay public section

    Find here your dedicated section

    Join the microbiota community

    • Facebook
    • Twitter
    • LinkedIn
    • YouTube

    © 2022 Biocodex. All rights reserved.

    • Cookies Policy
    • Data protection policy
    • GTU
    • Sitemap
    • Cookies settings
    Biocodex logo