Disorders related to disruption of microbiota | Biocodex Microbiote Institute

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Dysbiosis

Various events can affect the colonization of the human body by microbes and impact the implementation of a healthy microbiota in infants. In adulthood, this ecosystem can be disrupted by environmental and behavioral factors (antibiotics, lifestyle, stress, etc.).

This dysbiosis phenomenon has been observed in a certain number of diseases. Digestive, ENT or psychological problems, respiratory infections, metabolic or cutaneous disease, etc.

What is dysbiosis?

Dysbiosis is an imbalance between microbiota and its host and results from changes in the composition of bacterial flora. It is related to several different diseases. In a healthy person (host), microbial flora (or microbiota) is an ensemble of microorganisms, bacteria, fungi, and viruses living together in a perfectly structured, harmonious system. The host and their microbiota have a very close relationship, and interact so that each one functions appropriately.

Factors that favor it

Various events can disturb this equilibrium:

•   Medical treatments (particularly antibiotics),
•   Viral, bacterial, or parasitic infections
•   Immune deficits
•   Various diseases
•   Harsh changes in environment or diet
•   Stress

All of these factors can cause more or less lasting changes: harmful microbes (pathobionts) can become dominant, protective microbes can become more rare, and microbiota diversity becomes less rich.

Dysbiosis, cause or effect of disease?

Dysbiosis has been described in the intestinal microbiota in various gastrointestinal and metabolic diseases. It may also be involved in certain neuropsychiatric and neurodegenerative disorders. However, researchers still don’t know if dysbiosis is a cause or an effect of these diseases. The leading hypothesis is that it’s a vicious cycle: dysbiosis is influenced by environmental and genetic factors, but it also plays a role in the onset and severity of these diseases.

Treating dysbiosis

To rebalance your microbiota, beneficial microorganisms are promoted through the consumption of probiotics, prebiotics, and synbiotics. That is called "affecting the microbiota". At the same time, dietary changes can be made, prioritizing foods high in fiber (artichokes, garlic, onions, etc.) and fermented foods (sauerkraut), which are sources of prebiotics. Finally, in the most serious cases, fecal transplant can be used to correct dysbiosis.

Disorders

Stomach ache, diarrhea, bloating, etc., these symptoms that we are all familiar with are common signs of digestive system disruption.

What role does the intestinal microbiota play in the occurrence of diseases related to the nervous system? This question currently attracts a great deal of interest among researchers, especially for the following pathologies.

The intestinal microbiota has not yet revealed all its secrets to us, especially when it is a question of understanding the causes and/or consequences that it could have in nutrition and metabolism.

Man or woman, young or older, a disruption in the intestinal microbiota can have effects on the urinary system.

Sneezing, runny nose ... pollens are not the only culprits! And while the intestinal microbiota also has its share of responsibility ...

In women, some intimate discomforts are caused by an imbalance in the intestinal microbiota.

How can the intestinal microbiota influence skin problems? Research has shown connections between the two.

Joint pain, rheumatism, etc., the intestinal microbiota is increasingly suspected and investigated in this matter.

From colds to chronic asthma, exploration of the intestinal microbiota provides a new clarification on respiratory diseases.

One of the roles of the intestinal microbiota is to stimulate immunity. When this is disrupted, the consequences can be major.

How diet, lifestyle and intestinal microbiota can all be involved in circulatory and heart disorders.

Voir Digestive system Voir Psychiatry and nervous system Voir Nutrition and metabolism Voir Urinary system Voir Allergies Voir The genitals Voir The skin Voir Bones and joints Voir ENT and respiratory system Voir Immune system Voir Heart and blood vessels

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