Skip to main content
About the Institute
  • English
  • Français
  • Español
  • Russian
  • Portuguese
  • Polish

Breadcrumb

  1. Home
  2. Our marvelous microbiota
  3. Allergic rhinitis: get out the tissues and follow the dysbiosis
  • Learn all about microbiota
    • The gut microbiota
    • The ENT microbiota
    • The pulmonary microbiota
    • The urinary microbiota
    • The skin microbiota
    • The vaginal microbiota
  • Microbiota and related conditions
    • Digestive disorders
    • Women disorders
    • Metabolic disorders
    • Skin disorders
    • Pediatric disorders
    • Psychiatric disorders
    • Neurological disorders
    • Respiratory disorders
    • Urinary disorders
  • Act on your microbiota
    • Probiotics
    • Prebiotics
    • Fecal Microbiota Transplant
    • Diet
  • Publications
    • Thematics folders
    • News
    • Press room
    About the Institute

    Join the microbiota community

    • Facebook
    • Twitter
    • YouTube

Healthcare professionals section

Find here your dedicated section
Biocodex logo
The power of your gut
My microbiota as a woman
Our marvelous microbiota

Breadcrumb

  1. Home
  2. Our marvelous microbiota
  3. Allergic rhinitis: get out the tissues and follow the dysbiosis
Our marvelous microbiota

Allergic rhinitis: get out the tissues and follow the dysbiosis

Allergic rhinitis
The ENT microbiota Allergic rhinitis

Although we have a long way to go before discovering all its secrets, we do know that allergic rhinitis is associated with a respiratory microbiota imbalance. Better characterizing this dysbiosis may help us to develop targeted and individualized treatments.

The power of your gut
My microbiota as a woman
Our marvelous microbiota
  • Learn all about microbiota
    • The gut microbiota
    • The ENT microbiota
    • The pulmonary microbiota
    • The urinary microbiota
    • The skin microbiota
    • The vaginal microbiota
  • Microbiota and related conditions
    • Digestive disorders
    • Women disorders
    • Metabolic disorders
    • Skin disorders
    • Pediatric disorders
    • Psychiatric disorders
    • Neurological disorders
    • Respiratory disorders
    • Urinary disorders
  • Act on your microbiota
    • Probiotics
    • Prebiotics
    • Fecal Microbiota Transplant
    • Diet
  • Publications
    • Thematics folders
    • News
    • Press room
    About the Institute

    Join the microbiota community

    • Facebook
    • Twitter
    • YouTube

Healthcare professionals section

Find here your dedicated section
Biocodex logo

Sources

This article is based on scientific information

Sharing is caring

Your friends might be interested in this topic. Why not share it?

  • Facebook
  • Twitter
  • Mail

About this article

Created 08 April 2022
Updated 12 April 2022

Spring goes hand in hand with... sneezing! Itching, tingling, a runny nose, watery eyes... every year, the arrival of spring and high concentrations of pollen bring hay fever back with a bang. Allergic rhinitis—commonly known as hay fever—and its succession of symptoms plague the lives of (sidenote: Cheng L, Chen J, Fu Q, et al. Chinese Society of Allergy Guidelines for Diagnosis and Treatment of Allergic Rhinitis. Allergy Asthma Immunol Res (2018) 10(4):300–53.  Eifan AO, Durham SR. Pathogenesis of Rhinitis. Clin Exp Allergy (2016) 46 (9):1139–51. ) . This complex condition results from a combination of genetic and environmental factors, including an interaction between a respiratory microbiota imbalance and an abnormal and excessive immune system response. But what are the effects of this dysbiosis? And which microorganisms are involved?

40% Allergic rhinitis is thought to affect up to 40% of the world’s population, with a high prevalence.

1 person in 4 in industrialized countries.

An unbalanced respiratory microbiota

To find out, a Chinese team compared respiratory microbiota in nasal samples taken from 28 people suffering from acute episodes of seasonal allergic rhinitis with those of 15 non-allergic subjects. They found no difference between the two groups in terms of microorganism diversity and abundance, but important disparities in their composition. The bacterial genera Moraxella, Haemophilus, Streptococcus and Flavobacterium, predominant in the respiratory microbiota of healthy individuals, had been replaced in allergic individuals by the genera Klebsiella, Prevotella and Staphylococcus. In total, the researchers identified 10 bacterial genera that were over-represented in the latter.

Hay fever

Hay fever (or allergic rhinitis) is a very common chronic condition that affects both children and adults. 

It is an inflammatory disease of the nasal mucosa that is accompanied by one or more nasal symptoms, including nasal pruritus (itching, tingling), sneezing, rhinorrhea (runny nose) and nasal congestion (runny nose).

A disturbed metabolism 

The scientists then applied serum metabolomics, a technique that consists in analyzing the concentration of (sidenote: Metabolites Small molecules produced during cellular or bacterial metabolism. For example, short-chain fatty acids are metabolites produced by intestinal microbiota during fermentation of non-digestible complex carbohydrates (fibers, etc.). Silva YP, Bernardi A, Frozza RL. The Role of Short-Chain Fatty Acids From Gut Microbiota in Gut-Brain Communication. Front Endocrinol (Lausanne). 2020;11:25.  Lamichhane S, Sen P, Dickens AM, et al An overview of metabolomics data analysis: current tools and future perspectives. Comprehensive analytical chemistry. 2018 ; 82: 387-413 ) in serum. This revealed the presence of 26 different metabolites in allergic people compared to healthy people. They also discovered the presence of 16 altered metabolic pathways, including those of arachidonic acids, already known to produce inflammatory mediators involved in some inflammatory diseases, such as allergic asthma.

The ENT microbiota

Find out more

Hope for individualized treatments?

The combined results of these two approaches confirm the hypothesis that inflammatory reactions of allergic origin influence the balance of respiratory microbiota. More importantly, they provide important candidate biomarkers of potential use in the diagnosis of allergic rhinitis. The authors therefore suggest continuing this work to refine the identification of different subtypes of allergic rhinitis (seasonal/perennial, intermittent/persistent, mild/moderate/severe), which may pave the way for the development of individualized treatments... and an end to the ordeal of thousands of people.

Sources

Yuan Y., Wang C., Wang Q., et al. Airway Microbiome and Serum Metabolomics Analysis Identify Differential Candidate Biomarkers in Allergic Rhinitis. Front Immunol. 2022 Jan 5;12:771136

Tags
ENT Allergic rhinitis Dysbiosis

en_view en_sources

    See also

    Allergic rhinitis: the first months of life are key
    Allergies: the role of intrauterine life
    Created 08 April 2022
    Updated 12 April 2022

    About this article

    To know more about this topic.

    Main topic

    Allergic rhinitis

    Related microbiotas

    The ENT microbiota

    Related topics

    Allergic rhinitis
    Our marvelous microbiota

    Prebiotics: what you need to know

    With just one different letter separating prebiotics and probiotics, no wonder they get confused! To muddy ...

    Find out more

    Probiotics

    Probiotics: essential information for understanding and choosing them correctly. What exactly are probiotic...

    Find out more

    The ENT microbiota

    The ENT (ear, nose, throat) microbiota is made up of three distinct bacterial floras: the oral microbiota, ...

    Find out more

    Urinary disorders

    Find out more

    Respiratory disorders

    Find out more

    Psychiatric disorders

    Find out more

    Skin disorders

    Find out more

    The skin microbiota

    The skin microbiota: why is it so important?

    Find out more

    Latest news

    News
    Antibiotics: what impact on the microbiota and on our health?
    12.10.2022

    Antibiotics: what impact on the microbiota and on our health?

    Read the article
    Nature and microbiota: how does it affect your health?
    08.07.2022

    Nature and microbiota: how does it affect your health?

    Read the article
    Actu GP : Règles douloureuses : et si le microbiote vaginal était en cause ?
    15.06.2021

    Is the vaginal microbiota to blame for painful periods?

    Read the article
     Microbiote urétral : des infections urinaires masculines mieux comprises
    06.01.2023

    Urethral microbiota: a better understanding of male urinary tract infections

    Read the article
    03.11.2021

    Antibiotic resistance: an odd “souvenir” from exotic destinations

    Read the article
    Actu GP : Microbiote, asthme et antibiotique : une histoire de nez !
    13.10.2020

    Microbiota, asthma and antibiotics: it’s all in the nose!

    Read the article
    22.11.2021

    Antibiotics and neurodevelopmental disorders: does the microbiota play a role?

    Read the article
    28.10.2021

    6 things you should know about antibiotics

    Read the article
    My health, my microbiota
    Follow our Facebook page
    My microbiota as a woman
    Read more to know the different things you can do to keep your vaginal microbiota balanced
    Find your dedicated section
    Healthcare professionals
    • Learn all about microbiota
      • The gut microbiota
      • The ENT microbiota
      • The pulmonary microbiota
      • The urinary microbiota
      • The skin microbiota
      • The vaginal microbiota
    • Microbiota and related conditions
      • Digestive disorders
      • Women disorders
      • Metabolic disorders
      • Skin disorders
      • Pediatric disorders
      • Psychiatric disorders
      • Neurological disorders
      • Respiratory disorders
      • Urinary disorders
    • Act on your microbiota
      • Probiotics
      • Prebiotics
      • Fecal Microbiota Transplant
      • Diet
    • Publications
      • Thematics folders
      • News
      • Press room
      About the Institute

      Join the microbiota community

      • Facebook
      • Twitter
      • YouTube

    Healthcare professionals section

    Find here your dedicated section
    Biocodex logo
    The power of your gut
    My microbiota as a woman
    Our marvelous microbiota
    • English
    • Français
    • Español
    • Russian
    • Portuguese
    • Polish

    Browse the site

    • Learn all about microbiota
      • The gut microbiota
      • The ENT microbiota
      • The pulmonary microbiota
      • The urinary microbiota
      • The skin microbiota
      • The vaginal microbiota
    • Microbiota and related conditions
      • Digestive disorders
      • Women disorders
      • Metabolic disorders
      • Skin disorders
      • Pediatric disorders
      • Psychiatric disorders
      • Neurological disorders
      • Respiratory disorders
      • Urinary disorders
    • Act on your microbiota
      • Probiotics
      • Prebiotics
      • Fecal Microbiota Transplant
      • Diet
    • Publications
      • Thematics folders
      • News
      • Press room
      About the Institute

      Join the microbiota community

      • Facebook
      • Twitter
      • YouTube

    Healthcare professionals section

    Find here your dedicated section
    Biocodex logo

    Discover

    The power of your gut
    My microbiota as a woman
    Our marvelous microbiota

    Join the microbiota community

    • Facebook
    • Twitter
    • YouTube

    Healthcare professionals section

    Find here your dedicated section

    Redirection

    You are about to be redirected and leave our website

    • Be redirected
    • Stay on the Biocodex Microbiota Institute's website

    Stay with us !

    Join the microbiota community and receive "The Essentials" once a month to stay up to date with the latest news on the microbiota.

    * Mandatory Fields

    BMI 20-35

    Explore

    25.01.2023

    Fermented vegetables: good reasons to include them in your diet

    Read the article
    Insomnie chez les personnes âgées : le microbiote intestinal impliqué ?
    19.01.2023

    Insomnia in the elderly: are gut microbiota to blame?

    Read the article
    16.01.2023

    Schizophrenia: when following your gut leads to aggression

    Read the article

    Stay updated

    Join the Microbiota Community and receive once a month “The Essential” to stay up to date on the latest news about microbiota.

    * Mandatory Fields

    BMI 20-35

    • Learn all about microbiota
      • The gut microbiota
      • The ENT microbiota
      • The pulmonary microbiota
      • The urinary microbiota
      • The skin microbiota
      • The vaginal microbiota
    • Microbiota and related conditions
      • Digestive disorders
      • Women disorders
      • Metabolic disorders
      • Skin disorders
      • Pediatric disorders
      • Psychiatric disorders
      • Neurological disorders
      • Respiratory disorders
      • Urinary disorders
    • Act on your microbiota
      • Probiotics
      • Prebiotics
      • Fecal Microbiota Transplant
      • Diet
    • Publications
      • Thematics folders
      • News
      • Press room
      About the Institute

      Join the microbiota community

      • Facebook
      • Twitter
      • YouTube

    Healthcare professionals section

    Find here your dedicated section
    Biocodex logo

    Discover

    The power of your gut
    My microbiota as a woman
    Our marvelous microbiota

    Healthcare professionals section

    Find here your dedicated section

    Join the microbiota community

    • Facebook
    • Twitter
    • YouTube

    © 2022 Biocodex. All rights reserved.

    • Cookies Policy
    • Data protection policy
    • GTU
    • Sitemap
    • Cookies settings
    Biocodex logo