Skip to main content
About the Institute
  • English
  • Français
  • Español
  • Russian

Breadcrumb

  1. Home
  2. Fecal microbiota transplant
  3. Functional gastrointestinal disorders
  • Learn all about microbiota
    • The gut microbiota
    • The ENT microbiota
    • The pulmonary microbiota
    • The urinary microbiota
    • The skin microbiota
    • The vaginal microbiota
  • Microbiota and related conditions
    • Digestive disorders
    • Women disorders
    • Metabolic disorders
    • Skin disorders
    • Pediatric disorders
    • Psychiatric disorders
    • Neurological disorders
    • Respiratory disorders
    • Urinary disorders
  • Act on your microbiota
    • Probiotics
    • Prebiotics
    • Fecal Microbiota Transplant
    • Diet
  • Publications
    • Thematics folders
    • News
    • Press room
    About the Institute

    Join the microbiota community

    • Facebook
    • Twitter
    • YouTube

Healthcare professionals section

Find here your dedicated section
Biocodex logo
The power of your gut
My microbiota as a woman
Our marvelous microbiota

Breadcrumb

  1. Home
  2. Fecal microbiota transplant
  3. Functional gastrointestinal disorders
The power of your gut

Functional gastrointestinal disorders

Functional gastrointestinal disorders
The gut microbiota Fecal transplant

There are many names for these diseases: irritable bowel syndrome (IBS), spastic colitis, colopathy or even functional gastrointestinal disorders (FGID). However, it is not just a semantic issue. In all cases, the quality of life of the patient is significantly impacted.

The power of your gut
My microbiota as a woman
Our marvelous microbiota
  • Learn all about microbiota
    • The gut microbiota
    • The ENT microbiota
    • The pulmonary microbiota
    • The urinary microbiota
    • The skin microbiota
    • The vaginal microbiota
  • Microbiota and related conditions
    • Digestive disorders
    • Women disorders
    • Metabolic disorders
    • Skin disorders
    • Pediatric disorders
    • Psychiatric disorders
    • Neurological disorders
    • Respiratory disorders
    • Urinary disorders
  • Act on your microbiota
    • Probiotics
    • Prebiotics
    • Fecal Microbiota Transplant
    • Diet
  • Publications
    • Thematics folders
    • News
    • Press room
    About the Institute

    Join the microbiota community

    • Facebook
    • Twitter
    • YouTube

Healthcare professionals section

Find here your dedicated section
Biocodex logo

Sources

This article is based on scientific information

Sharing is caring

Your friends might be interested in this topic. Why not share it?

  • Facebook
  • Twitter
  • Mail

Sections

About this article

Created 19 December 2019
Updated 29 December 2021

The microbiota of patients with irritable bowel syndrome is less diversified and shows greater abundance of enterobacteria, but with a lower content in bifidobacteria and lactobacilli. Functional gastrointestinal disorders are characterized by a decreased production of butyrate and an increased production of acetic and propionic acids, which are three substances associated with bloating. Abdominal pain, diarrhea and constipation are other symptoms of these disorders. In the US, an estimated 20% of the population is affected14.

Controversial effects

Aside from ulcerative colitis, irritable bowel syndrome is the only other gastrointestinal condition for which a treatment with fecal microbiota transplant has been studied in clinical trials14. One of them showed a decrease in intestinal discomfort, abdominal pain and flatulence in transplant recipients. However, the results varied depending on the initial nature of the gut microbiota: the best responders to fecal microbiota transplant had an initial high content of Streptococci and they had a greater increase in biodiversity. Other works confirm the increased diversity and abundance of the microbiota after the administration of fecal matter capsules; however, patients reported a better improvement in symptoms when they received... placebo! Although these results do not undermine the efficacy of FMT in people with functional gastrointestinal disorders, detailed microbiota analyses before and after the transplant are necessary, according to the researchers.

What about constipation?

Constipation is potentially associated to gut dysbiosis and has been the focus of several works aiming at assessing the usefulness of FMT in this transit disorder13. In a study conducted in about sixty adults suffering from slow transit that compared the standard treatment to 6 courses of FMT, the latter was shown to cause a significant improvement of symptoms and transit, and more generally, in the quality of life15. These encouraging results still need to be confirmed: studies are also ongoing with specific strains, lactobacilli and bifidobacteria13.

Sources

13 Maladies inflammatoires chroniques de l’Intestin (MICI). Inserm. Fév. 2016

14 D’Haens GR, Jobin C. Fecal Microbial Transplantation For Diseases Beyond Recurrent Clostridium Difficile Infection. Gastroenterology. 2019 June

15 Tom Holvoet, et al. Fecal Microbiota Transplantation in Irritable Bowel Syndrome with Predominant Abdominal Bloating: Results from a Double Blind, Placebo-Controlled Clinical Trial. Gastroenterology. 2018

en_view en_sources

    See also

    Image1_Article5_DTO Fecal transplant: a promising route?
    Actu GP : Mieux définir les banques de selles pour déployer la greffe Improving the definition of stool banks to promote the widespread adoption of FMT
    Focus
    Fecal microbiota transplant
    • What is FMT?
      • The mechanism of FMT: transplanting to restore the balance
      • FMT, in practice: from the donor to the side effects
    • Proven efficacity for a single indication
      • Recurrent Clostridium difficile colitis: the only validated indication
    • What about tomorrow
      • Chronic inflammatory bowel diseases
      • Functional gastrointestinal disorders
      • Hepatic encephalopathy
      • Metabolic disorders
      • Expert Interview : Pr Harry Sokol
    Created 19 December 2019
    Updated 29 December 2021

    About this article

    To know more about this topic.

    Main topic

    Functional gastrointestinal disorders

    Related microbiotas

    The gut microbiota

    Related topics

    Fecal transplant
    Chronic inflammatory bowel diseases
    Hepatic encephalopathy
    Focus

    Fecal microbiota transplant

    What is FMT?

    The mechanism of FMT: transplanting to restore the balance FMT, in practice: from the donor to the side effects

    Proven efficacity for a single indication

    Recurrent Clostridium difficile colitis: the only validated indication

    What about tomorrow

    Chronic inflammatory bowel diseases Functional gastrointestinal disorders Hepatic encephalopathy Metabolic disorders Expert Interview : Pr Harry Sokol
    The power of your gut
    La discrimination difficile à digérer
    20.03.2023

    How discrimination turns our stomach

    Read the article

    Pediatric disorders

    Find out more
    Actu GP : Schizophrénie et microbiote : un lien confirmé ?
    28.05.2019

    Schizophrenia and microbiota: has the link been confirmed?

    Read the article

    How our gut constantly talks to our brain

    Our gut, often called our “second brain”, owns 200 million neurons (enteric nervous system), hosts several ...

    Find out more
    Periods and endometriosis: what is the role of the microbiota?
    24.01.2023

    Periods and endometriosis: what is the role of the microbiota?

    Read the article
    28.02.2023

    Why running could bring a smile to depressed teens... and their gut microbiota

    Read the article
    16.05.2022

    Gut microbiota: still many things to be discovered

    Read the article
    Patients stories - logo
    21.11.2022

    Patients stories: living with irritable bowel syndrome (IBS)

    Read the article
    My health, my microbiota
    Follow our Facebook page
    Our marvelous microbiota
    Get to understand our microbiota and the role they play in our body
    Find your dedicated section
    Healthcare professionals
    • Learn all about microbiota
      • The gut microbiota
      • The ENT microbiota
      • The pulmonary microbiota
      • The urinary microbiota
      • The skin microbiota
      • The vaginal microbiota
    • Microbiota and related conditions
      • Digestive disorders
      • Women disorders
      • Metabolic disorders
      • Skin disorders
      • Pediatric disorders
      • Psychiatric disorders
      • Neurological disorders
      • Respiratory disorders
      • Urinary disorders
    • Act on your microbiota
      • Probiotics
      • Prebiotics
      • Fecal Microbiota Transplant
      • Diet
    • Publications
      • Thematics folders
      • News
      • Press room
      About the Institute

      Join the microbiota community

      • Facebook
      • Twitter
      • YouTube

    Healthcare professionals section

    Find here your dedicated section
    Biocodex logo
    The power of your gut
    My microbiota as a woman
    Our marvelous microbiota
    • English
    • Français
    • Español
    • Russian

    Browse the site

    • Learn all about microbiota
      • The gut microbiota
      • The ENT microbiota
      • The pulmonary microbiota
      • The urinary microbiota
      • The skin microbiota
      • The vaginal microbiota
    • Microbiota and related conditions
      • Digestive disorders
      • Women disorders
      • Metabolic disorders
      • Skin disorders
      • Pediatric disorders
      • Psychiatric disorders
      • Neurological disorders
      • Respiratory disorders
      • Urinary disorders
    • Act on your microbiota
      • Probiotics
      • Prebiotics
      • Fecal Microbiota Transplant
      • Diet
    • Publications
      • Thematics folders
      • News
      • Press room
      About the Institute

      Join the microbiota community

      • Facebook
      • Twitter
      • YouTube

    Healthcare professionals section

    Find here your dedicated section
    Biocodex logo

    Discover

    The power of your gut
    My microbiota as a woman
    Our marvelous microbiota

    Join the microbiota community

    • Facebook
    • Twitter
    • YouTube

    Healthcare professionals section

    Find here your dedicated section

    Redirection

    You are about to be redirected and leave our website

    • Be redirected
    • Stay on the Biocodex Microbiota Institute's website

    Stay with us !

    Join the microbiota community and receive "The Essentials" once a month to stay up to date with the latest news on the microbiota.

    * Mandatory Fields

    BMI 20-35

    Explore

    La discrimination difficile à digérer
    20.03.2023

    How discrimination turns our stomach

    Read the article
    14.03.2023

    Does microbiota play a role in infertility?

    Read the article
    How to keep a healthy microbiota?
    02.03.2023

    How to keep a healthy microbiota?

    Read the article

    Stay updated

    Join the Microbiota Community and receive once a month “The Essential” to stay up to date on the latest news about microbiota.

    * Mandatory Fields

    BMI 20-35

    • Learn all about microbiota
      • The gut microbiota
      • The ENT microbiota
      • The pulmonary microbiota
      • The urinary microbiota
      • The skin microbiota
      • The vaginal microbiota
    • Microbiota and related conditions
      • Digestive disorders
      • Women disorders
      • Metabolic disorders
      • Skin disorders
      • Pediatric disorders
      • Psychiatric disorders
      • Neurological disorders
      • Respiratory disorders
      • Urinary disorders
    • Act on your microbiota
      • Probiotics
      • Prebiotics
      • Fecal Microbiota Transplant
      • Diet
    • Publications
      • Thematics folders
      • News
      • Press room
      About the Institute

      Join the microbiota community

      • Facebook
      • Twitter
      • YouTube

    Healthcare professionals section

    Find here your dedicated section
    Biocodex logo

    Discover

    The power of your gut
    My microbiota as a woman
    Our marvelous microbiota

    Healthcare professionals section

    Find here your dedicated section

    Join the microbiota community

    • Facebook
    • Twitter
    • YouTube

    © 2022 Biocodex. All rights reserved.

    • Cookies Policy
    • Data protection policy
    • GTU
    • Sitemap
    • Cookies settings
    Biocodex logo