Improving the definition of stool banks to promote the widespread adoption of FMT
On June 22, 2019, several international experts in fecal microbiota transplant–or stool transplant–met in Rome to come to an agreement regarding the direction that should be given to stool banks and provide a Good Practice Guide with the purpose of promoting the availability of this technique.
About this article
Fecal microbiota transplant (FMT) is now a recognized treatment for recurrent Clostridium difficile infection (CDI), but it is not thriving the way it should. This could be due to the lack of specialized centers, difficulties to recruit donors or complexity of procedures. By reducing hospital administrative burden, stool banks could help the widespread adoption of this technique. However, their legislation, organization and structure are too diverse to provide everyone with the same guarantees.
Around thirty experts came together to establish a single definition of stool banks and prepare a Good Practice Guide. After reviewing the scientific literature, they reached a consensus on 6 topics: 1) general principles of FMT and stool bank; 2) selection and screening of donors; 3) collection, preparation and storage of stools; 4) services and clients; 5) records, result monitoring and ethical issues; 6) update of clinical applications of FMT.
The only validated indication for FMT is recurrent Clostridioides difficile infection. This practice may present health risks and must be performed under medical supervision, do not reproduce at home!
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Cammarota G, Ianiro G, Kelly Colleen R. et al. International consensus conference on stool banking for faecal microbiota transplantation in clinical practice. Gut 2019; 68: 2111–2121.