Skip to main content
About the Institute
  • English
  • Français
  • Español
  • Russian
  • Portuguese
  • Polish

Breadcrumb

  1. Home
  2. Our marvelous microbiota
  3. Pomegranate to the rescue of disrupted skin microbiota
  • Learn all about microbiota
    • The gut microbiota
    • The ENT microbiota
    • The pulmonary microbiota
    • The urinary microbiota
    • The skin microbiota
    • The vaginal microbiota
  • Microbiota and related conditions
    • Digestive disorders
    • Women disorders
    • Metabolic disorders
    • Skin disorders
    • Pediatric disorders
    • Psychiatric disorders
    • Neurological disorders
    • Respiratory disorders
    • Urinary disorders
  • Act on your microbiota
    • Probiotics
    • Prebiotics
    • Fecal Microbiota Transplant
    • Diet
  • Publications
    • News
    • Thematics folders
    • Thematic pages
    • Microbiota Q & A
    • Patients Stories
    • Experts' point of view
  • About the Institute
    • About us
    • International Microbiota Observatory
    • Press room
    • Partnerships

    Join the microbiota community

    • Facebook
    • Twitter
    • LinkedIn
    • YouTube
    • Instagram
    • Bluesky

Healthcare professionals section

Find here your dedicated section
Biocodex logo
The power of your gut
My microbiota as a woman
Our marvelous microbiota

Breadcrumb

  1. Home
  2. Our marvelous microbiota
  3. Pomegranate to the rescue of disrupted skin microbiota
Our marvelous microbiota

Pomegranate to the rescue of disrupted skin microbiota

Skin health
The skin microbiota Psoriasis and microbiota Acne and microbiota Allergic eczema Skin disorders

Pomegranate contains substances that may contribute to rebalancing the populations of micro-organisms living on the surface of our skin. Researchers have shown that an extract of the peel weakens pathogenic bacteria and reinforces beneficial bacteria.

The power of your gut
My microbiota as a woman
Our marvelous microbiota
  • Learn all about microbiota
    • The gut microbiota
    • The ENT microbiota
    • The pulmonary microbiota
    • The urinary microbiota
    • The skin microbiota
    • The vaginal microbiota
  • Microbiota and related conditions
    • Digestive disorders
    • Women disorders
    • Metabolic disorders
    • Skin disorders
    • Pediatric disorders
    • Psychiatric disorders
    • Neurological disorders
    • Respiratory disorders
    • Urinary disorders
  • Act on your microbiota
    • Probiotics
    • Prebiotics
    • Fecal Microbiota Transplant
    • Diet
  • Publications
    • News
    • Thematics folders
    • Thematic pages
    • Microbiota Q & A
    • Patients Stories
    • Experts' point of view
  • About the Institute
    • About us
    • International Microbiota Observatory
    • Press room
    • Partnerships

    Join the microbiota community

    • Facebook
    • Twitter
    • LinkedIn
    • YouTube
    • Instagram
    • Bluesky

Healthcare professionals section

Find here your dedicated section
Biocodex logo

Sources

This article is based on scientific information

Sharing is caring

Your friends might be interested in this topic. Why not share it?

  • Facebook
  • Twitter
  • Mail

About this article

Created 08 November 2024
Updated 15 November 2024

A natural, non-toxic and ecologically responsible product that improves the equilibrium of the skin microbiota and helps fight against skin problems: you thought it was a dream? A team of Italian researchers has done it...using pomegranate skins that were about to be thrown away! 1

This inedible part makes up 50% of the fruit. It usually ends up in the trash during the manufacture of pomegranate juice and extracts. However, it contains the majority of the precious polyphenols found in pomegranate, some of which possess antibacterial properties that are of interest for health.

02.08.2021 The skin microbiota Read more

The Italian researchers wanted to know whether, by making using of these peels to extract their precious components, it would be possible to develop a product capable of re-establishing the equilibrium of the skin microbiota and improving skin health.

The battle: good bacteria vs. bad bacteria

Dysbiosis of the skin microbiota, characterized by the proliferation of pathogenic bacteria to the detriment of beneficial bacteria, has been implicated in numerous skin problems, such as acne, psoriasis and atopic dermatitis.

Skin disorders

Learn more

The researchers first took samples of the skin microbiota from the skin of 9 young volunteers, 3 of whom suffered from skin problems linked to atopic dermatitis. From these samples, they extracted:

  • Staphylococcus aureus, pathogenic bacteria responsible for skin dysbiosis
  • Staphylococcus epidermidis, known for its beneficial effects and its ability to restore the integrity of the skin barrier.

Meanwhile, the scientists prepared an extract of pomegranate peel (Punica granatum L.) using energy-saving extraction methods and recyclable solvents. 

After verifying that it was non-toxic, they placed the product in contact with the bacteria taken from the volunteers.

19.03.2024 How S. aureus bacteria are trying to get under your skin Read more

Twofold effect of pomegranate

The result: the pomegranate extract has both a significant antimicrobial effect on the pathogenic S. aureus and a protective effect on the beneficial S. epidermidis. 

For the researchers, these effects are most likely connected to the phenolic components of pomegranate: catechins, quercetin, gallic acid, etc. These act in a targeted manner, on the one hand preventing pathogenic bacteria from sticking to the skin and forming protective biofilms, and on the other hand stimulating the ability of beneficial bacteria to synthesize biofilms. 

Neutralizing the enemy is an art!

Everyone has the harmful Staphylococcus aureus on the surface of their skin. Most of the time, however, it does not proliferate.

Why? Because the “good” bacteria of the skin microbiota secrete an ultra-sophisticated arsenal of formidable small molecules (bacteriocins, antibiotics, short-chain fatty acids, antimicrobial peptides, etc.) capable of blocking the multiplication of Staphylococcus aureus and inhibiting its proliferation.

In addition, by regulating the inflammatory response, contributing to the homeostasis of skin cells and maintaining the integrity of the epidermis, good bacteria contribute to microbial equilibrium. Nice, but strong!

Clinical trials will need to be carried out before it is possible to confirm the ability of this extract to prevent, alleviate or cure skin problems, particularly those linked to antimicrobial-resistant bacteria. 

If the results are positive, this would provide further evidence that it is possible to integrate the health of the ecosystem with human health using a “One health” 2 approach.

Sources

1. D’Arcangelo S, Di Fermo P, Diban F, et al. Staphylococcus aureus/Staphylococcus epidermidis from skin microbiota are balanced by Pomegranate peel extract: An eco-sustainable approach. PLoS One. 2024 Aug 1;19(8):e0308211.

2. https://www.who.int/fr/news-room/fact-sheets/detail/one-health

Tags
Skin microbiota Acne Psoriasis Atopic Dermatitis Dysbiosis Microbiome Flora

    See also

    Photo: Dermatite atopique : il faut sauver la peau du champignon Malassezia Atopic dermatitis: protecting the skin from the Malassezia fungus
    Like to tan? Mind your skin microbiota!
    Created 08 November 2024
    Updated 15 November 2024

    About this article

    To know more about this topic.

    Main topic

    Skin health

    Related microbiotas

    The skin microbiota

    Related topics

    Psoriasis and microbiota Acne and microbiota Allergic eczema Skin disorders
    Our marvelous microbiota

    Microbiotalk : short conferences on antimicrobial resistance

    Breaking the silence: a global conversation on antimicrobial resistance Antimicrobial resistance (AM...

    Find out more

    The skin microbiota

    The skin microbiota: why is it so important?

    Find out more

    The pulmonary microbiota

    Why is the lung microbiota so important for health? Researchers long held the view that the lungs of...

    Find out more

    The gut microbiota

    Gut microbiota: why is it that important for your health? We have trillions1 of bacteria that po...

    Find out more

    Fecal transplant

    Fecal transplant involves introducing a healthy person’s stool into a patient’s digestive tract in or...

    Find out more

    Acne and microbiota

    Acne, which is a very common skin disease during adolescence, is caused by hormonal changes associate...

    Find out more

    Psoriasis and microbiota

    Psoriasis is a skin disease of inflammatory origin, caused by the epidermis renewing itself too quick...

    Find out more

    Prebiotics: what you need to know

    With just one different letter separating prebiotics and probiotics, no wonder they get confused! To ...

    Find out more

    Latest news

    News
    Allergies : et si tout venait du microbiote ?
    28.03.2023

    Allergies: and what if it all started with the microbiota?

    Read the article
    03.04.2025

    Groundbreaking study: every home has unique water microbiome

    Read the article
    11.05.2021

    Dust microbiota from the city or the countryside? Atopic dermatitis has a preference!

    Read the article
    15.03.2022

    Greening of daycare centers and microbiota: flower power!

    Read the article
    Actu GP : Vaginose bactérienne : les hommes seraient-ils impliqués ?
    24.11.2020

    Are men involved in bacterial vaginosis?

    Read the article
    Actu PRO : Dermatite atopique : les microbiotes nasal et cutané associés à la sévérité
    27.01.2021

    Atopic dermatitis: the skin microbiome has an accomplice!

    Read the article
    12.03.2025

    Do fungi in the nose play a role in rhinitis and asthma?

    Read the article
    Actu GP : Les espaces verts urbains, bons pour nos microbiotes ?
    22.12.2020

    Are urban green spaces good for our microbiota?

    Read the article
    • Learn all about microbiota
      • The gut microbiota
      • The ENT microbiota
      • The pulmonary microbiota
      • The urinary microbiota
      • The skin microbiota
      • The vaginal microbiota
    • Microbiota and related conditions
      • Digestive disorders
      • Women disorders
      • Metabolic disorders
      • Skin disorders
      • Pediatric disorders
      • Psychiatric disorders
      • Neurological disorders
      • Respiratory disorders
      • Urinary disorders
    • Act on your microbiota
      • Probiotics
      • Prebiotics
      • Fecal Microbiota Transplant
      • Diet
    • Publications
      • News
      • Thematics folders
      • Thematic pages
      • Microbiota Q & A
      • Patients Stories
      • Experts' point of view
    • About the Institute
      • About us
      • International Microbiota Observatory
      • Press room
      • Partnerships

      Join the microbiota community

      • Facebook
      • Twitter
      • LinkedIn
      • YouTube
      • Instagram
      • Bluesky

    Healthcare professionals section

    Find here your dedicated section
    Biocodex logo
    The power of your gut
    My microbiota as a woman
    Our marvelous microbiota
    • English
    • Français
    • Español
    • Russian
    • Portuguese
    • Polish

    Browse the site

    • Learn all about microbiota
      • The gut microbiota
      • The ENT microbiota
      • The pulmonary microbiota
      • The urinary microbiota
      • The skin microbiota
      • The vaginal microbiota
    • Microbiota and related conditions
      • Digestive disorders
      • Women disorders
      • Metabolic disorders
      • Skin disorders
      • Pediatric disorders
      • Psychiatric disorders
      • Neurological disorders
      • Respiratory disorders
      • Urinary disorders
    • Act on your microbiota
      • Probiotics
      • Prebiotics
      • Fecal Microbiota Transplant
      • Diet
    • Publications
      • News
      • Thematics folders
      • Thematic pages
      • Microbiota Q & A
      • Patients Stories
      • Experts' point of view
    • About the Institute
      • About us
      • International Microbiota Observatory
      • Press room
      • Partnerships

      Join the microbiota community

      • Facebook
      • Twitter
      • LinkedIn
      • YouTube
      • Instagram
      • Bluesky

    Healthcare professionals section

    Find here your dedicated section
    Biocodex logo

    Discover

    The power of your gut
    My microbiota as a woman
    Our marvelous microbiota

    Join the microbiota community

    • Facebook
    • Twitter
    • LinkedIn
    • YouTube
    • Instagram
    • Bluesky

    Healthcare professionals section

    Find here your dedicated section

    Redirection

    You are about to be redirected and leave our website

    • Be redirected
    • Stay on the Biocodex Microbiota Institute's website

    Stay with us !

    Join the microbiota community and receive "The Essentials" once a month to stay up to date with the latest news on the microbiota.

    * Mandatory Fields

    BMI 20-35

    Explore

    13.05.2025

    When sodas harm your microbiota and your health

    Read the article
    07.05.2025

    Downside of fruit and vegetable juices for gut health

    Read the article
    Photo LP: Sensibles à l’E466 ? Votre microbiote a son mot à dire
    15.04.2025

    Sensitive to E466? Your microbiota plays a role

    Read the article

    Stay updated

    Join the Microbiota Community and receive once a month “The Essential” to stay up to date on the latest news about microbiota.

    * Mandatory Fields

    BMI 20-35

    • Learn all about microbiota
      • The gut microbiota
      • The ENT microbiota
      • The pulmonary microbiota
      • The urinary microbiota
      • The skin microbiota
      • The vaginal microbiota
    • Microbiota and related conditions
      • Digestive disorders
      • Women disorders
      • Metabolic disorders
      • Skin disorders
      • Pediatric disorders
      • Psychiatric disorders
      • Neurological disorders
      • Respiratory disorders
      • Urinary disorders
    • Act on your microbiota
      • Probiotics
      • Prebiotics
      • Fecal Microbiota Transplant
      • Diet
    • Publications
      • News
      • Thematics folders
      • Thematic pages
      • Microbiota Q & A
      • Patients Stories
      • Experts' point of view
    • About the Institute
      • About us
      • International Microbiota Observatory
      • Press room
      • Partnerships

      Join the microbiota community

      • Facebook
      • Twitter
      • LinkedIn
      • YouTube
      • Instagram
      • Bluesky

    Healthcare professionals section

    Find here your dedicated section
    Biocodex logo

    Discover

    The power of your gut
    My microbiota as a woman
    Our marvelous microbiota

    Healthcare professionals section

    Find here your dedicated section

    Join the microbiota community

    • Facebook
    • Twitter
    • LinkedIn
    • YouTube
    • Instagram
    • Bluesky

    © 2025 Biocodex. All rights reserved.

    • Legal notice
    • GTU
    • Data protection policy
    • Sitemap
    • Cookies settings
    • Digital accessibility : partially compliant
    Biocodex logo