chronic fatigue syndrome: a question of microbiota?

Chronic fatigue syndrome, the neurological disease that is characterized by a state of persistent fatigue even after rest, could be linked to an imbalance of the intestinal microbiota, according to a study published in Microbiome.

Also called myalgic encephalomyelitis, chronic fatigue syndrome occurs between age 20 and 40, especially in women. In addition to continuous fatigue, patients suffer from sleep disorders, cognitive disorders and 35 to 90% have abdominal pain similar to irritable bowel syndrome.

Intrigued by this similarity, researchers compared the stool of patients to that of healthy subjects and observed an overrepresentation of some types of bacteria in these patients. The authors assert that dysbiosis influences the severity of the syndrome. They hope that this discovery will improve the diagnosis of this disorder and lead to the development of new therapeutic strategies.



Microbiome April 2017 doi:10.1186/s40168-017-0261-y Fecal metagenomic profiles in subgroups of patients with myalgic encephalomyelitis/chronic fatigue syndrome