Skip to main content
About the Institute
  • English
  • Français
  • Español
  • Russian
  • Portuguese
  • Polish

Breadcrumb

  1. Home
  2. Our marvelous microbiota
  3. Osteoarthritis: when gut dysbiosis jams the joints
  • Learn all about microbiota
    • The gut microbiota
    • The ENT microbiota
    • The pulmonary microbiota
    • The urinary microbiota
    • The skin microbiota
    • The vaginal microbiota
  • Microbiota and related conditions
    • Digestive disorders
    • Women disorders
    • Metabolic disorders
    • Skin disorders
    • Pediatric disorders
    • Psychiatric disorders
    • Neurological disorders
    • Respiratory disorders
    • Urinary disorders
  • Act on your microbiota
    • Probiotics
    • Prebiotics
    • Fecal Microbiota Transplant
    • Diet
  • Publications
    • News
    • Thematics folders
    • Thematic pages
    • Microbiota Q & A
    • Patients Stories
    • Experts' point of view
  • About the Institute
    • About us
    • International Microbiota Observatory
    • Press room
    • Partnerships

    Join the microbiota community

    • Facebook
    • Twitter
    • LinkedIn
    • YouTube
    • Instagram
    • Bluesky

Healthcare professionals section

Find here your dedicated section
Biocodex logo
The power of your gut
My microbiota as a woman
Our marvelous microbiota

Breadcrumb

  1. Home
  2. Our marvelous microbiota
  3. Osteoarthritis: when gut dysbiosis jams the joints
Our marvelous microbiota

Osteoarthritis: when gut dysbiosis jams the joints

Osteoarthritis
The gut microbiota

World Osteoarthritis Day is held every year on September 17 to discuss and raise awareness on this disease that causes joint deformity. Could the solution lie in our gut microbiota as suggested by recent studies carried out on elderly women?

The power of your gut
My microbiota as a woman
Our marvelous microbiota
  • Learn all about microbiota
    • The gut microbiota
    • The ENT microbiota
    • The pulmonary microbiota
    • The urinary microbiota
    • The skin microbiota
    • The vaginal microbiota
  • Microbiota and related conditions
    • Digestive disorders
    • Women disorders
    • Metabolic disorders
    • Skin disorders
    • Pediatric disorders
    • Psychiatric disorders
    • Neurological disorders
    • Respiratory disorders
    • Urinary disorders
  • Act on your microbiota
    • Probiotics
    • Prebiotics
    • Fecal Microbiota Transplant
    • Diet
  • Publications
    • News
    • Thematics folders
    • Thematic pages
    • Microbiota Q & A
    • Patients Stories
    • Experts' point of view
  • About the Institute
    • About us
    • International Microbiota Observatory
    • Press room
    • Partnerships

    Join the microbiota community

    • Facebook
    • Twitter
    • LinkedIn
    • YouTube
    • Instagram
    • Bluesky

Healthcare professionals section

Find here your dedicated section
Biocodex logo

Sources

This article is based on scientific information

Sharing is caring

Your friends might be interested in this topic. Why not share it?

  • Facebook
  • Twitter
  • Mail

About this article

Created 25 October 2021
Updated 31 August 2023
Reading time 2min

Osteoarthritis, a condition that makes joints seize up and become misshapen, blights the life of more than 3% of the world’s population, especially seniors. 10% of men and 18% of women over 60 are suffering from this painful and debilitating joint disease. It has multiple causes: genetics, gender, age, obesity, sedentary lifestyle… and maybe even the gut microbiota. We already know that our gut bacteria are involved in several inflammatory diseases, and they might also play a role in osteoarthritis-related inflammation.

How an unbalanced gut microbiota correlates with osteoarthritis

To learn more about the relationship between gut microbiota and osteoarthritis in elderly women, researchers compared the stool bacterial composition of 57 women aged 65 on average suffering from osteoarthritis and that of 57 healthy volunteers of the same age (control). The gut microbiota of patients with osteoarthritis was generally less abundant and less diversified. Some beneficial bacteria are less prevalent, such as Bifidobacterium longum which regulates the immune system, or Faecalibacterium prausnitzii, an anti-inflammatory bacterium known for its health benefits in humans. On the contrary, the content of some pathogenic bacteria such as Clostridium ramosum is increased. In addition, some functions of the gut microbiota seem to be disrupted in case of osteoarthritis, thus suggesting a reduced ability to benefit from food.

When could the gut microbiota help with diagnosis, and even treatment?


Since the gut microbiota of patients with osteoarthritis is different from that of controls–thus suggesting that the gut microbiota could be a risk factor–the research team tried to develop a predictive tool for the disease based on the presence of 9 bacteria in the patients’ stools. Their predictive model was proven reliable in the elderly women from the study but has not yet been verified in other patient groups. The presence of these bacteria could well prove to be useful in establishing a diagnosis. These microorganisms could also open up new treatment options for osteoarthritis based on prebiotics or probiotics. Ultimately this could lead to better pain relief and improved quality of life for osteoarthritis patients.

Recommended by our community

"A very interesting article. Might be worth checking further. I have osteoarthritis plus IBS. Wonder if there is a correlation!" - Patricia Benner

"Thank you for this info!!" - Shirley Dorion

"Interesting! I believe the gut is connected to many health problems!" - Anita Randmaa Clarke

(From My health, my microbiota)

Source

Chen J, Wang A, Wang Q. Dysbiosis of the gut microbiome is a risk factor for osteoarthritis in older female adults: a case control study. BMC Bioinformatics. 2021 Jun 3;22(1):299.

Tags
Osteoarthritis Gut microbiota Dysbiosis Microbiome Flora

    See also

    Is the gut microbiota a good indicator of longevity?
    Actu GP : Infections urinaires récurrentes a la ménopause, la faute au microbiote de la vessie ? Is the bladder microbiota responsible for recurrent urinary tract infections in postmenopausal women?
    Created 25 October 2021
    Updated 31 August 2023
    Reading time 2min

    About this article

    To know more about this topic.

    Main topic

    Osteoarthritis

    Related microbiotas

    The gut microbiota
    Our marvelous microbiota

    Microbiotalk : short conferences on antimicrobial resistance

    Breaking the silence: a global conversation on antimicrobial resistance Antimicrobial resistance (AM...

    Find out more

    The skin microbiota

    The skin microbiota: why is it so important?

    Find out more

    The pulmonary microbiota

    Why is the lung microbiota so important for health? Researchers long held the view that the lungs of...

    Find out more

    The gut microbiota

    Gut microbiota: why is it that important for your health? We have trillions1 of bacteria that po...

    Find out more

    Fecal transplant

    Fecal transplant involves introducing a healthy person’s stool into a patient’s digestive tract in or...

    Find out more

    Acne and microbiota

    Acne, which is a very common skin disease during adolescence, is caused by hormonal changes associate...

    Find out more

    Psoriasis and microbiota

    Psoriasis is a skin disease of inflammatory origin, caused by the epidermis renewing itself too quick...

    Find out more

    Prebiotics: what you need to know

    With just one different letter separating prebiotics and probiotics, no wonder they get confused! To ...

    Find out more

    Latest news

    News
    Allergies : et si tout venait du microbiote ?
    28.03.2023

    Allergies: and what if it all started with the microbiota?

    Read the article
    03.04.2025

    Groundbreaking study: every home has unique water microbiome

    Read the article
    11.05.2021

    Dust microbiota from the city or the countryside? Atopic dermatitis has a preference!

    Read the article
    15.03.2022

    Greening of daycare centers and microbiota: flower power!

    Read the article
    Actu GP : Vaginose bactérienne : les hommes seraient-ils impliqués ?
    24.11.2020

    Are men involved in bacterial vaginosis?

    Read the article
    Actu PRO : Dermatite atopique : les microbiotes nasal et cutané associés à la sévérité
    27.01.2021

    Atopic dermatitis: the skin microbiome has an accomplice!

    Read the article
    12.03.2025

    Do fungi in the nose play a role in rhinitis and asthma?

    Read the article
    Actu GP : Les espaces verts urbains, bons pour nos microbiotes ?
    22.12.2020

    Are urban green spaces good for our microbiota?

    Read the article
    • Learn all about microbiota
      • The gut microbiota
      • The ENT microbiota
      • The pulmonary microbiota
      • The urinary microbiota
      • The skin microbiota
      • The vaginal microbiota
    • Microbiota and related conditions
      • Digestive disorders
      • Women disorders
      • Metabolic disorders
      • Skin disorders
      • Pediatric disorders
      • Psychiatric disorders
      • Neurological disorders
      • Respiratory disorders
      • Urinary disorders
    • Act on your microbiota
      • Probiotics
      • Prebiotics
      • Fecal Microbiota Transplant
      • Diet
    • Publications
      • News
      • Thematics folders
      • Thematic pages
      • Microbiota Q & A
      • Patients Stories
      • Experts' point of view
    • About the Institute
      • About us
      • International Microbiota Observatory
      • Press room
      • Partnerships

      Join the microbiota community

      • Facebook
      • Twitter
      • LinkedIn
      • YouTube
      • Instagram
      • Bluesky

    Healthcare professionals section

    Find here your dedicated section
    Biocodex logo
    The power of your gut
    My microbiota as a woman
    Our marvelous microbiota
    • English
    • Français
    • Español
    • Russian
    • Portuguese
    • Polish

    Browse the site

    • Learn all about microbiota
      • The gut microbiota
      • The ENT microbiota
      • The pulmonary microbiota
      • The urinary microbiota
      • The skin microbiota
      • The vaginal microbiota
    • Microbiota and related conditions
      • Digestive disorders
      • Women disorders
      • Metabolic disorders
      • Skin disorders
      • Pediatric disorders
      • Psychiatric disorders
      • Neurological disorders
      • Respiratory disorders
      • Urinary disorders
    • Act on your microbiota
      • Probiotics
      • Prebiotics
      • Fecal Microbiota Transplant
      • Diet
    • Publications
      • News
      • Thematics folders
      • Thematic pages
      • Microbiota Q & A
      • Patients Stories
      • Experts' point of view
    • About the Institute
      • About us
      • International Microbiota Observatory
      • Press room
      • Partnerships

      Join the microbiota community

      • Facebook
      • Twitter
      • LinkedIn
      • YouTube
      • Instagram
      • Bluesky

    Healthcare professionals section

    Find here your dedicated section
    Biocodex logo

    Discover

    The power of your gut
    My microbiota as a woman
    Our marvelous microbiota

    Join the microbiota community

    • Facebook
    • Twitter
    • LinkedIn
    • YouTube
    • Instagram
    • Bluesky

    Healthcare professionals section

    Find here your dedicated section

    Redirection

    You are about to be redirected and leave our website

    • Be redirected
    • Stay on the Biocodex Microbiota Institute's website

    Stay with us !

    Join the microbiota community and receive "The Essentials" once a month to stay up to date with the latest news on the microbiota.

    * Mandatory Fields

    BMI 20-35

    Explore

    13.05.2025

    When sodas harm your microbiota and your health

    Read the article
    07.05.2025

    Downside of fruit and vegetable juices for gut health

    Read the article
    Photo LP: Sensibles à l’E466 ? Votre microbiote a son mot à dire
    15.04.2025

    Sensitive to E466? Your microbiota plays a role

    Read the article

    Stay updated

    Join the Microbiota Community and receive once a month “The Essential” to stay up to date on the latest news about microbiota.

    * Mandatory Fields

    BMI 20-35

    • Learn all about microbiota
      • The gut microbiota
      • The ENT microbiota
      • The pulmonary microbiota
      • The urinary microbiota
      • The skin microbiota
      • The vaginal microbiota
    • Microbiota and related conditions
      • Digestive disorders
      • Women disorders
      • Metabolic disorders
      • Skin disorders
      • Pediatric disorders
      • Psychiatric disorders
      • Neurological disorders
      • Respiratory disorders
      • Urinary disorders
    • Act on your microbiota
      • Probiotics
      • Prebiotics
      • Fecal Microbiota Transplant
      • Diet
    • Publications
      • News
      • Thematics folders
      • Thematic pages
      • Microbiota Q & A
      • Patients Stories
      • Experts' point of view
    • About the Institute
      • About us
      • International Microbiota Observatory
      • Press room
      • Partnerships

      Join the microbiota community

      • Facebook
      • Twitter
      • LinkedIn
      • YouTube
      • Instagram
      • Bluesky

    Healthcare professionals section

    Find here your dedicated section
    Biocodex logo

    Discover

    The power of your gut
    My microbiota as a woman
    Our marvelous microbiota

    Healthcare professionals section

    Find here your dedicated section

    Join the microbiota community

    • Facebook
    • Twitter
    • LinkedIn
    • YouTube
    • Instagram
    • Bluesky

    © 2025 Biocodex. All rights reserved.

    • Legal notice
    • GTU
    • Data protection policy
    • Sitemap
    • Cookies settings
    • Digital accessibility : partially compliant
    Biocodex logo