What to take away? Respiratory immunity
About this article
The bidirectional communication axis between the gut and lungs, called the “gut–lung axis” influences the immune status of both organs.
Lung and gut microbiota influence each other and may have an impact on respiratory diseases.4
1 1 factor known to control vaccine efficacy can be gut microbiota.(5)
4 Sencio V, Machado MG, Trottein F. The lung-gut axis during viral respiratory infections: the impact of gut dysbiosis on secondary disease outcomes. Mucosal Immunol. 2021 Mar;14(2):296-304.
5 Lynn DJ, Benson SC, Lynn MA, et al. Modulation of immune responses to vaccination by the microbiota: implications and potential mechanisms. Nat Rev Immunol. 2021 May 17:1–14.
6 Dumas A, Bernard L, Poquet Y, et al. The role of the lung microbiota and the gut-lung axis in respiratory infectious diseases. Cell Microbiol. 2018 Dec;20(12):e12966.
7 Levy M, Kolodziejczyk AA, Thaiss CA, et al. Dysbiosis and the immune system. Nat Rev Immunol. 2017;17(4):219-232.