Pediatrics

What to take away? Skin immunity

Immunity

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Created 24 November 2021
Updated 22 July 2024

Skin and gut dysbiosis, as well as immune dysregulation, have been observed in the development of atopic dermatitis, a complex disease with multifactorial causes.8

2 Atopic dermatitis is characterized by the activation of type 2 lymphocytes resulting in an overactive and exaggerated immune response.(9)

INFLAMMATION

Atopic dermatitis is a chronic inflammatory skin disease that appears in periodic flare-ups.9 The inflammation observed is the result of an immune dysregulation.9

Sources

8 Sugita K, Akdis CA. Recent developments and advances in atopic dermatitis and food allergy. Allergol Int. 2020 Apr;69(2):204-214. 

9 Langan SM, Irvine AD, Weidinger S. Atopic dermatitis. Lancet. 2020 Aug 1;396(10247):345-360.

Tags
Atopic Dermatitis Immunity Gut-skin axis Skin microbiota Gut microbiota Flare-up Dysbiosis Staphylococcus aureus Dermatology Microbiome Flora
    Focus

    Microbiota, a diplomatic immunity?

    Introduction

    Understanding the complex interplay between the microbiota and immunity is only just beginning

    Intestinal Immunity

    The infant's gut at the heart of immunity Factors influencing microbiota development and maturation of the immune system early in life The impact of western diet on the mucus layer Dampening gastrointestinal inflammation through nutrition

    Gut microbiota influences respiratory immunity

    The gut microbiota is involved in the lung’s defense against viral respiratory infections Gut-lung axis in viral respiratory infections The hygiene hypothesis and the COVID-19 pandemic Targeting the gut microbiota to optimize vaccine efficacy?

    Role of the microbiota in skin immunity and atopic dermatitis

    Expert interview: Pr. Brigitte Dréno

    Conclusion

    What to take away? Intestinal Immunity What to take away? Respiratory immunity What to take away? Skin immunity

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